Literature DB >> 23903082

Giant congenital melanocytic nevus: report from 30 years of experience in a single department.

Bo Sonnich Rasmussen1, Trine Foged Henriksen, Stig-Frederik Trojahn Kølle, Grethe Schmidt.   

Abstract

Giant congenital melanocytic nevi (GCMN) occur in 1:20,000 livebirths and are associated with increased risk of malignant transformation. The treatment of GCMN from 1981 to 2010 in a tertiary referral center was reviewed evaluating the modalities used, cosmetic results, associated complications, and malignant transformation. Of 35 patients, 25 underwent surgery. Curettage was most frequently used (64%) followed by excision and tissue expansion (20%). Six percent of the patients treated with curettage, and 78% of the patients who received excision surgery required more than 1 planned procedure, and 25% versus 44% required unplanned additional surgery, respectively. Complications were noted in 25% and 67% of the patients, respectively. Cosmetic result was satisfying in 76% of patients without difference between the groups. No malignant transformation was found during a mean follow-up of 11 years. Curettage is a gentle alternative to excision with a lower complication rate and good cosmetic outcome.

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Year:  2015        PMID: 23903082     DOI: 10.1097/SAP.0b013e3182920c3d

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  5 in total

1.  A case report of the first application of culture epithelial autograft (JACE®) for giant congenital melanocytic nevus after its approval in Japan.

Authors:  Naoki Morimoto; Natsuko Kakudo; Ayako Kako; Keiko Nishimura; Toshihito Mitsui; Ryohei Miyake; Atsuyuki Kuro; Masakatsu Hihara; Kenji Kusumoto
Journal:  J Artif Organs       Date:  2017-11-17       Impact factor: 1.731

2.  Cultured epithelial autografts for the treatment of large-to-giant congenital melanocytic nevus in 31 patients.

Authors:  Naoki Morimoto; Toshihito Mitsui; Yasuhiro Katayama; Natsuko Kakudo; Shuichi Ogino; Itaru Tsuge; Michiharu Sakamoto; Masakatsu Hihara; Kenji Kusumoto
Journal:  Regen Ther       Date:  2021-07-15       Impact factor: 3.419

3.  Neonatal Curettage of Large to Giant Congenital Melanocytic Nevi Under Local Anesthetic: A Case Series With Long-Term Follow Up.

Authors:  Laura C Soong; Alma Bencivenga; Loretta Fiorillo
Journal:  J Cutan Med Surg       Date:  2021-11-18       Impact factor: 2.092

4.  Serial Tissue Expansion at the Same Site in Pediatric Patients: Is the Subsequent Expansion Faster?

Authors:  Moon Ki Lee; Seong Oh Park; Tae Hyun Choi
Journal:  Arch Plast Surg       Date:  2017-10-26

5.  Efficacy of Cultured Epithelial Autograft after Curettage for Giant Melanocytic Nevus of the Head.

Authors:  Tamami Maeda; Naoki Morimoto; Natsuko Kakudo; Kenji Kusumoto
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-06-19
  5 in total

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