| Literature DB >> 2390155 |
Abstract
The effect of pH on the pain of administration and efficacy of 1% lignocaine was investigated in a prospective, double-blind, randomized study of 20 adult volunteers. Onset and spread of anaesthesia by intra-dermal injection were not altered, but there was a significant reduction in pain scores with a higher pH. Overall, pain scores appear to be more dependent on the speed of injection rather than alteration of pH.Entities:
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Year: 1990 PMID： 2390155 PMCID： PMC1285669 DOI： 10.1136/emj.7.2.65
Source DB: PubMed Journal: Arch Emerg Med ISSN： 0264-4924