| Literature DB >> 23900493 |
Vincenza Barresi1, Carmela Bonaccorso, Giuseppe Consiglio, Laura Goracci, Nicolò Musso, Giuseppe Musumarra, Cristina Satriano, Cosimo G Fortuna.
Abstract
A dataset of 50 compounds was used to generate a QSAR model and to design 9 new heteroaryl ethylenes. These compounds were synthesized, tested in vitro and a significant agreement with in silico predictions observed. Studies using Laser Scanning Confocal Microscopy pointed out that the compounds may act by different mechanisms.Entities:
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Year: 2013 PMID： 23900493 DOI： 10.1039/c3mb70151d
Source DB: PubMed Journal: Mol Biosyst ISSN： 1742-2051