Literature DB >> 23900491

IBX mediated reaction of β-enamino esters with allylic alcohols: a one pot metal free domino approach to functionalized pyridines.

Narendar Reddy Gade1, V Devendram, Manojit Pal, Javed Iqbal.   

Abstract

IBX facilitated the reaction of β-enamino esters with allylic alcohols affording a direct, one-pot and metal free synthesis of functionalized pyridines including 2-substituted nicotinic acids, densely substituted pyridines and precursors of azafluorenones. The methodology also afforded the racemic pyridine core of cyclothiazomycin.

Entities:  

Year:  2013        PMID: 23900491     DOI: 10.1039/c3cc44274h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  DABCO- and DBU-promoted one-pot reaction of N-sulfonyl ketimines with Morita-Baylis-Hillman carbonates: a sequential approach to (2-hydroxyaryl)nicotinate derivatives.

Authors:  Soumitra Guin; Raman Gupta; Debashis Majee; Sampak Samanta
Journal:  Beilstein J Org Chem       Date:  2018-11-02       Impact factor: 2.883

Review 2.  IBX-Mediated Organic Transformations in Heterocyclic Chemistry-A Decade Update.

Authors:  Yadavalli Venkata Durga Nageswar; Katla Ramesh; Katla Rakhi
Journal:  Front Chem       Date:  2022-02-28       Impact factor: 5.221

  2 in total

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