Literature DB >> 23900405

Nonmedical use of prescription ADHD stimulant medications among adults in a substance abuse treatment population: early findings from the NAVIPPRO surveillance system.

Theresa A Cassidy1, Emily C McNaughton2, Sajan Varughese3, Leo Russo3, Mirella Zulueta2, Stephen F Butler2.   

Abstract

OBJECTIVE: To examine nonmedical use (NMU) of prescription ADHD stimulants among adults evaluated for substance abuse treatment.
METHOD: 147,816 assessments from the National Addictions Vigilance Intervention and Prevention Program (NAVIPPRO) system (10/01/2009 through 03/31/2012) examined NMU prevalence, routes of administration (ROA), and diversion sources.
RESULTS: Past 30-day NMU for prescription stimulants (1.29%) was significantly lower than that of prescription opioids (19.79%) or sedatives (10.62%). For stimulant products, NMU for Adderall was 0.62, followed by Adderall XR (0.42), Ritalin (0.16), Vyvanse (0.12), and Concerta (0.08); product differences likely have limited clinical relevance given the low estimates (<1%). Higher NMU per prescriptions was for Adderall (4.92), Ritalin (4.68), and Adderall XR (3.18) compared with newer formulations (Vyvanse 1.26, Concerta 0.89). Diversion source was mainly family/friends with no differences between products; swallowing whole was the most frequent ROA.
CONCLUSION: Prescription stimulant NMU was low compared with other prescription medications among individuals assessed for substance abuse problems, with little difference among specific products.
© 2013 SAGE Publications.

Entities:  

Keywords:  ADHD; NAVIPPRO; nonmedical use; prescription stimulants; substance abuse

Mesh:

Substances:

Year:  2013        PMID: 23900405     DOI: 10.1177/1087054713493321

Source DB:  PubMed          Journal:  J Atten Disord        ISSN: 1087-0547            Impact factor:   3.256


  6 in total

1.  Characterizing prescription stimulant nonmedical use (NMU) among adults recruited from Reddit.

Authors:  Suzanne K Vosburg; Rebekkah S Robbins; Kevin M Antshel; Stephen V Faraone; Jody L Green
Journal:  Addict Behav Rep       Date:  2021-09-11

Review 2.  A systematic review of the safety of lisdexamfetamine dimesylate.

Authors:  David R Coghill; Beatriz Caballero; Shaw Sorooshian; Richard Civil
Journal:  CNS Drugs       Date:  2014-06       Impact factor: 5.749

3.  Shopping behavior for ADHD drugs: results of a cohort study in a pharmacy database.

Authors:  M Soledad Cepeda; Daniel Fife; Joris Berwaerts; Yingli Yuan; Greg Mastrogiovanni
Journal:  Drugs R D       Date:  2014-09

4.  Long-term study of lisdexamfetamine dimesylate in Japanese children and adolescents with attention-deficit/hyperactivity disorder.

Authors:  Hironobu Ichikawa; Tasuku Miyajima; Yushiro Yamashita; Masakazu Fujiwara; Akimasa Fukushi; Kazuhiko Saito
Journal:  Neuropsychopharmacol Rep       Date:  2019-12-08

5.  Relative Abuse of Crush-Resistant Prescription Opioid Tablets via Alternative Oral Modes of Administration.

Authors:  Stephen F Butler; Ryan A Black; Alison B Fleming
Journal:  Pain Med       Date:  2018-08-01       Impact factor: 3.750

6.  Phase II/III Study of Lisdexamfetamine Dimesylate in Japanese Pediatric Patients with Attention-Deficit/Hyperactivity Disorder.

Authors:  Hironobu Ichikawa; Tasuku Miyajima; Yushiro Yamashita; Masakazu Fujiwara; Akimasa Fukushi; Kazuhiko Saito
Journal:  J Child Adolesc Psychopharmacol       Date:  2019-11-12       Impact factor: 2.576

  6 in total

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