Literature DB >> 23899281

A common cause of irritable bowel syndrome and diverticulitis: chronic distal colon distention from sedentary behavior and excessive dietary fiber.

Steven E Robbins1.   

Abstract

A multidisciplinary analysis restricted to validated reports was applied to the cause and management of irritable bowel syndrome and diverticular formation and subsequent diverticulitis. There is evidence that they are linked - both caused by attenuation of gravitational aid to distal intestinal motility, resulting in damaging chronic intestinal distention. Both irritable bowel syndrome and diverticular formation and subsequent diverticulitis have worsened in recent years owing to excessive dietary fiber intake. Potential solutions include augmenting weight-bearing time, moderating dietary fiber consumption, stimulating distal colon evacuation through chemical means and developing pharmaceuticals to block the reflexive distal colon distention associated with fiber consumption. Amplified intestinal distention commenced when all classes of Renaissance Europeans became the first group in human history to wear shoes, which led to a sedentary lifestyle that moderates gravitational aid to colon motility and evacuation.

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Year:  2013        PMID: 23899281     DOI: 10.1586/17474124.2013.811043

Source DB:  PubMed          Journal:  Expert Rev Gastroenterol Hepatol        ISSN: 1747-4124            Impact factor:   3.869


  2 in total

1.  Colon distention induces persistent visceral hypersensitivity by mechanotranscription of pain mediators in colonic smooth muscle cells.

Authors:  You-Min Lin; Yu Fu; Chester C Wu; Guang-Yin Xu; Li-Yen Huang; Xuan-Zheng Shi
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2014-12-24       Impact factor: 4.052

2.  Irritable brain caused by irritable bowel? A nationwide analysis for irritable bowel syndrome and risk of bipolar disorder.

Authors:  Chia-Jen Liu; Li-Yu Hu; Chiu-Mei Yeh; Yu-Wen Hu; Pan-Ming Chen; Tzeng-Ji Chen; Ti Lu
Journal:  PLoS One       Date:  2015-03-13       Impact factor: 3.240

  2 in total

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