Literature DB >> 23898850

Poor insight into schizophrenia: contributing factors, consequences and emerging treatment approaches.

Paul H Lysaker1, Jen Vohs, Jaclyn D Hillis, Marina Kukla, Raffaele Popolo, Giampaolo Salvatore, Giancarlo Dimaggio.   

Abstract

Poor insight or unawareness of illness has been commonly observed in schizophrenia and has been long recognized as a potent barrier to treatment adherence and a risk factor for a range of poorer outcomes. Paradoxically, the achievement of insight often poses a different set of problems including depression and low self-esteem. One barrier to the treatment of poor insight has been a lack of understanding of the phenomenon, which causes poor insight to develop and persist over time. Without knowing what promotes poor insight, treatment to date has had little to offer beyond the supportive provision of information. To explore these issues, this article reviews emerging literature on the correlates of poor insight in schizophrenia, and newly developing ways of conceptualizing insight. It then details a number of innovative integrative group and individual treatment approaches in the early stages of development, which take into account some of the potential causal forces behind poor insight, including deficits in neurocognition, social cognition, metacognition and heightened self-stigma. A plan for further research is presented to develop a model of the factors whose interaction influences insight, and to refine and test integrative treatments.

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Year:  2013        PMID: 23898850     DOI: 10.1586/14737175.2013.811150

Source DB:  PubMed          Journal:  Expert Rev Neurother        ISSN: 1473-7175            Impact factor:   4.618


  25 in total

1.  The impact of cognitive insight, self-stigma, and medication compliance on the quality of life in patients with schizophrenia.

Authors:  Yin-Ju Lien; Hsin-An Chang; Yu-Chen Kao; Nian-Sheng Tzeng; Chien-Wen Lu; Ching-Hui Loh
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2017-07-29       Impact factor: 5.270

2.  Insight, self-stigma and psychosocial outcomes in Schizophrenia: a structural equation modelling approach.

Authors:  Y-J Lien; H-A Chang; Y-C Kao; N-S Tzeng; C-W Lu; C-H Loh
Journal:  Epidemiol Psychiatr Sci       Date:  2016-12-15       Impact factor: 6.892

3.  Cognitive insight and objective quality of life in people with schizophrenia and auditory hallucinations.

Authors:  Ruchika Rathee; Tanya M Luhrmann; Triptish Bhatia; Smita N Deshpande
Journal:  Psychiatry Res       Date:  2017-09-13       Impact factor: 3.222

4.  Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.

Authors:  Paul H Lysaker; Michelle L Pattison; Bethany L Leonhardt; Scott Phelps; Jenifer L Vohs
Journal:  World Psychiatry       Date:  2018-02       Impact factor: 49.548

5.  The Neuropsychiatric Approach to the Assessment of Patients in Neurology.

Authors:  Nicholas T Trapp; Michael R Martyna; Shan H Siddiqi; Sepideh N Bajestan
Journal:  Semin Neurol       Date:  2022-04-27       Impact factor: 3.212

6.  The "Insight Paradox" in Schizophrenia: Magnitude, Moderators and Mediators of the Association Between Insight and Depression.

Authors:  Martino Belvederi Murri; Mario Amore; Pietro Calcagno; Matteo Respino; Valentina Marozzi; Mattia Masotti; Michele Bugliani; Marco Innamorati; Maurizio Pompili; Silvana Galderisi; Mario Maj
Journal:  Schizophr Bull       Date:  2016-04-11       Impact factor: 9.306

7.  Splitting in schizophrenia and borderline personality disorder.

Authors:  Ondrej Pec; Petr Bob; Jiri Raboch
Journal:  PLoS One       Date:  2014-03-06       Impact factor: 3.240

Review 8.  Nonadherence with antipsychotic medication in schizophrenia: challenges and management strategies.

Authors:  Peter M Haddad; Cecilia Brain; Jan Scott
Journal:  Patient Relat Outcome Meas       Date:  2014-06-23

9.  Validity of subjective versus objective quality of life assessment in people with schizophrenia.

Authors:  Karen P Hayhurst; Jennifer A Massie; Graham Dunn; Shôn W Lewis; Richard J Drake
Journal:  BMC Psychiatry       Date:  2014-12-24       Impact factor: 3.630

Review 10.  DSM-5: a collection of psychiatrist views on the changes, controversies, and future directions.

Authors:  Charles B Nemeroff; Daniel Weinberger; Michael Rutter; Harriet L MacMillan; Richard A Bryant; Simon Wessely; Dan J Stein; Carmine M Pariante; Florian Seemüller; Michael Berk; Gin S Malhi; Martin Preisig; Martin Brüne; Paul Lysaker
Journal:  BMC Med       Date:  2013-09-12       Impact factor: 8.775

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