OBJECTIVES: To evaluate the role of needle-core biopsy in the pathologic diagnosis of lymphoma. METHODS: One hundred and five cases with clinical suspicion for lymphoma were studied by 3 hematopathologists mimicking daily diagnostic service. The diagnostic result sheets were analyzed for diagnostic accuracy and reproducibility. The histologic pattern recognition by the 3 hematopathologists was also analyzed. RESULTS: The overall diagnostic accuracy, based on the consensus diagnosis, was 85% to 87%. High reproducibility of diagnosis in lymphoma was observed among pathologists. The tissue size was associated with the percentage of definitive diagnosis. Histologic patterns were well recognized on core tissues. CONCLUSIONS: Needle-core biopsy is an effective technique for the diagnosis of lymphoma and should be considered the first-line procedure for cases with suspicion for lymphoma.
OBJECTIVES: To evaluate the role of needle-core biopsy in the pathologic diagnosis of lymphoma. METHODS: One hundred and five cases with clinical suspicion for lymphoma were studied by 3 hematopathologists mimicking daily diagnostic service. The diagnostic result sheets were analyzed for diagnostic accuracy and reproducibility. The histologic pattern recognition by the 3 hematopathologists was also analyzed. RESULTS: The overall diagnostic accuracy, based on the consensus diagnosis, was 85% to 87%. High reproducibility of diagnosis in lymphoma was observed among pathologists. The tissue size was associated with the percentage of definitive diagnosis. Histologic patterns were well recognized on core tissues. CONCLUSIONS: Needle-core biopsy is an effective technique for the diagnosis of lymphoma and should be considered the first-line procedure for cases with suspicion for lymphoma.
Authors: Novella Pugliese; M Di Perna; I Cozzolino; G Ciancia; G Pettinato; P Zeppa; V Varone; S Masone; C Cerchione; R Della Pepa; L Simeone; C Giordano; V Martinelli; C Salvatore; F Pane; M Picardi Journal: Ann Hematol Date: 2017-01-27 Impact factor: 3.673