Literature DB >> 23896551

An unusual anatomic and geographic location of primary germinoma of the fourth ventricle.

Akbar A Khan1, Matthew A Kirkman, Caroline Anderson, Zane Jaunmuktane, Robert C Morris, Neil D Kitchen.   

Abstract

Intracranial germinoma is most commonly found in the pineal and suprasellar regions. The medulla oblongata and fourth ventricle are rare sites of primary germinoma, with only 12 previous patients reported, all from the Far East. To our knowledge, we report the first patient from Europe. A 25-year-old female of Afro-Caribbean origin presented with several weeks of worsening migraines, dizziness, tachycardia and veering to the right whilst walking. MRI revealed a lesion in the fourth ventricle, which was treated with surgical debulking and post operative radiotherapy. Two months following completion of radiotherapy, MRI showed almost complete resolution of the enhancing disease within the primary tumour area and no intraspinal pathological enhancement. This patient highlights the importance of considering germinoma in the differential diagnosis of all medullary masses with extension into the fourth ventricle irrespective of geographic location.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Europe; Fourth ventricle; Germinoma; Medulla

Mesh:

Year:  2013        PMID: 23896551     DOI: 10.1016/j.jocn.2012.11.025

Source DB:  PubMed          Journal:  J Clin Neurosci        ISSN: 0967-5868            Impact factor:   1.961


  2 in total

1.  Primary germinoma of the medulla oblongata: illustrative case.

Authors:  Pablo Albiña; Aracelly Solis; Jose Lorenzoni; Pablo Henny; María Manriquez
Journal:  J Neurosurg Case Lessons       Date:  2022-06-06

2.  Dyspnea and choking as presenting symptoms in primary medulla oblongata germinoma.

Authors:  Chi-Man Yip; Hui-Hwa Tseng; Shu-Shong Hsu; Wei-Chuan Liao; Jun-Yih Chen; Chih-Hao Chen; Chia-Yuan Chang
Journal:  Surg Neurol Int       Date:  2014-06-19
  2 in total

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