Literature DB >> 23895089

Insight view on possible role of fluoroquinolones in cancer therapy.

Prabodh C Sharma1, Monika Chaudhary, Archana Sharma, Mona Piplani, Harish Rajak, Om Prakash.   

Abstract

Cancer is a disease without limits turning out to be prime cause for raising death toll around the world. Several treatment strategies including chemotherapy, surgery and radiotherapy are being employed worldwide to combat this disease. Due to the unwanted effects of currently available therapies, scientific community is immensely interested in exploring newer alternative pathways. Fluoroquinolones have been employed as potent anti-microbial agents for last few decades and now being looked up as potential therapeutic agents in the other ailments also. Several research endeavours are carried out in different parts of the world to focus on the prospective role of fluoroquinolones in carcinogenesis and mutagenesis. This article is an earnest attempt to present recent research work carried out on fluoroquinolones in the context to cancer treatment therapies.

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Year:  2013        PMID: 23895089     DOI: 10.2174/15680266113139990133

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN: 1568-0266            Impact factor:   3.295


  3 in total

1.  Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives.

Authors:  G Franci; G Manfroni; R Cannalire; T Felicetti; O Tabarrini; A Salvato; M L Barreca; L Altucci; V Cecchetti
Journal:  Cell Prolif       Date:  2015-12       Impact factor: 6.831

2.  Synthesis and characterization of N-Mannich based prodrugs of ciprofloxacin and norfloxacin: In vitro anthelmintic and cytotoxic evaluation.

Authors:  Mona Piplani; Harish Rajak; Prabodh Chander Sharma
Journal:  J Adv Res       Date:  2017-06-13       Impact factor: 10.479

3.  7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation.

Authors:  Rukhsana Tabassum; Muhammad Ashfaq; Hiroyuki Oku
Journal:  Heliyon       Date:  2020-10-01
  3 in total

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