| Literature DB >> 23894153 |
Valérie Lallemand-Breitenbach1, Hugues de Thé.
Abstract
Rarely in the field of cancer treatment did we experience as many surprises as with acute promyelocytic leukemia (APL). Yet, the latest clinical trial reported by Lo-Coco et al in the New England Journal of Medicine is a practice-changing study, as it reports a very favorable outcome of virtually all enrolled low-intermediate risk patients with APL without any DNA-damaging chemotherapy. Although predicted from previous small pilot studies, these elegant and stringently controlled results open a new era in leukemia therapy.Entities:
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Year: 2013 PMID： 23894153 DOI： 10.1182/blood-2013-06-505115
Source DB: PubMed Journal: Blood ISSN： 0006-4971 Impact factor: 22.113