Literature DB >> 23893910

4-Hydroxyphenylpyruvate dioxygenase inhibitors in combination with safeners: solutions for modern and sustainable agriculture.

Hartmut Ahrens1, Gudrun Lange, Thomas Müller, Chris Rosinger, Lothar Willms, Andreas van Almsick.   

Abstract

Inhibitors of 4-hydroxyphenylpyruvate dioxygenase (HPPD) prevent plant carotenoid pigment formation, which in turn leads to chlorophyll degradation. This "bleaching" herbicide mode of action provides weed-control products for various crops, such as rice, corn, and cereals. Combinations with suitable safeners allow the full exploitation of the potential of this compound class to selectively control major weed problems, including rapidly increasing cases of resistance against other important herbicide classes.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  HPPD inhibitors; crop protection agents; drug discovery; herbicides; safeners

Mesh：

Substances：

Year:  2013        PMID： 23893910     DOI： 10.1002/anie.201302365

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  13 in total

1.  Free energy calculations elucidate substrate binding, gating mechanism, and tolerance-promoting mutations in herbicide target 4-hydroxyphenylpyruvate dioxygenase.

Authors:  Christina E M Schindler; Eva Hollenbach; Thomas Mietzner; Klaus-Jürgen Schleifer; Martin Zacharias
Journal:  Protein Sci       Date:  2019-04-19       Impact factor: 6.725

2.  Herbicides as weed control agents: state of the art: II. Recent achievements.

Authors:  Hansjoerg Kraehmer; Andreas van Almsick; Roland Beffa; Hansjoerg Dietrich; Peter Eckes; Erwin Hacker; Ruediger Hain; Harry John Strek; Hermann Stuebler; Lothar Willms
Journal:  Plant Physiol       Date:  2014-08-07       Impact factor: 8.340

3.  Design, microwave-assisted synthesis, bioactivity and SAR of novel substituted 2-phenyl-2-cyclohexanedione enol ester derivatives.

Authors:  Fei Ye; Peng Ma; Yue Zhai; Fei Yang; Shuang Gao; Li-Xia Zhao; Ying Fu
Journal:  RSC Adv       Date:  2018-05-29       Impact factor: 3.361

4.  Physiological and Molecular Mechanisms of Differential Sensitivity of Palmer Amaranth (Amaranthus palmeri) to Mesotrione at Varying Growth Temperatures.

Authors:  Amar S Godar; Vijaya K Varanasi; Sridevi Nakka; P V Vara Prasad; Curtis R Thompson; J Mithila
Journal:  PLoS One       Date:  2015-05-19       Impact factor: 3.240

Review 5.  Catalytic strategies of the non-heme iron dependent oxygenases and their roles in plant biology.

Authors:  Mark D White; Emily Flashman
Journal:  Curr Opin Chem Biol       Date:  2016-03-23       Impact factor: 8.822

6.  Combination of Virtual Screening Protocol by in Silico toward the Discovery of Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.

Authors:  Ying Fu; Yi-Na Sun; Ke-Han Yi; Ming-Qiang Li; Hai-Feng Cao; Jia-Zhong Li; Fei Ye
Journal:  Front Chem       Date:  2018-02-06       Impact factor: 5.221

7.  3D Pharmacophore-Based Virtual Screening and Docking Approaches toward the Discovery of Novel HPPD Inhibitors.

Authors:  Ying Fu; Yi-Na Sun; Ke-Han Yi; Ming-Qiang Li; Hai-Feng Cao; Jia-Zhong Li; Fei Ye
Journal:  Molecules       Date:  2017-06-09       Impact factor: 4.411

8.  Design, Synthesis, and Herbicidal Activity Evaluation of Novel Aryl-Naphthyl Methanone Derivatives.

Authors:  Ying Fu; Kui Wang; Peng Wang; Jing-Xin Kang; Shuang Gao; Li-Xia Zhao; Fei Ye
Journal:  Front Chem       Date:  2019-01-22       Impact factor: 5.221

9.  Design, Synthesis and Evaluation of Novel Trichloromethyl Dichlorophenyl Triazole Derivatives as Potential Safener.

Authors:  Ke-Liang Guo; Li-Xia Zhao; Zi-Wei Wang; Shu-Zhe Rong; Xiao-Lin Zhou; Shuang Gao; Ying Fu; Fei Ye
Journal:  Biomolecules       Date:  2019-09-01

10.  Based on the Virtual Screening of Multiple Pharmacophores, Docking and Molecular Dynamics Simulation Approaches toward the Discovery of Novel HPPD Inhibitors.

Authors:  Ying Fu; Tong Ye; Yong-Xuan Liu; Jian Wang; Fei Ye
Journal:  Int J Mol Sci       Date:  2020-08-03       Impact factor: 5.923
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