Literature DB >> 23893651

Total synthesis and structural revision of viridicatumtoxin B.

K C Nicolaou1, Christian Nilewski, Christopher R H Hale, Heraklidia A Ioannidou, Abdelatif ElMarrouni, Lizanne G Koch.   

Abstract

Entities:  

Keywords:  antibiotics; natural products; structural revision; tetracyclines; total synthesis

Mesh:

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Year:  2013        PMID: 23893651      PMCID: PMC3835450          DOI: 10.1002/anie.201304691

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  30 in total

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5.  A practical, convergent route to the key precursor to the tetracycline antibiotics.

Authors:  David A Kummer; Derun Li; Amelie Dion; Andrew G Myers
Journal:  Chem Sci       Date:  2011-09       Impact factor: 9.825

6.  Viridicatumtoxin, a new mycotoxin from Penicillium viridicatum Westling.

Authors:  R D Hutchison; P S Steyn; S J Van Rensburg
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7.  Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase.

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8.  Methodological Advances Permit the Stereocontrolled Construction of Diverse Fully Synthetic Tetracyclines Containing an All-Carbon Quaternary Center at Position C5a.

Authors:  Peter M Wright; Andrew G Myers
Journal:  Tetrahedron       Date:  2011-12-23       Impact factor: 2.457

9.  Spirohexalines, new inhibitors of bacterial undecaprenyl pyrophosphate synthase, produced by Penicillium brasilianum FKI-3368.

Authors:  Junji Inokoshi; Yuichiro Nakamura; Zhang Hongbin; Ryuji Uchida; Ken-ichi Nonaka; Rokuro Masuma; Hiroshi Tomoda
Journal:  J Antibiot (Tokyo)       Date:  2012-11-21       Impact factor: 2.649

10.  Formal synthesis of angiogenesis inhibitor NM-3.

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Journal:  Org Biomol Chem       Date:  2014-05-14       Impact factor: 3.876

2.  Inhibition of bacterial undecaprenyl pyrophosphate synthase by small fungal molecules.

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Review 3.  Natural Products as Platforms To Overcome Antibiotic Resistance.

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Review 4.  A brief history of antibiotics and select advances in their synthesis.

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6.  Asymmetric Alkylation of Anthrones, Enantioselective Total Synthesis of (-)- and (+)-Viridicatumtoxins B and Analogues Thereof: Absolute Configuration and Potent Antibacterial Agents.

Authors:  K C Nicolaou; Guodu Liu; Kathryn Beabout; Megan D McCurry; Yousif Shamoo
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7.  Recent total syntheses of anthraquinone-based natural products.

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Journal:  Tetrahedron       Date:  2022-01-11       Impact factor: 2.457

8.  A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis.

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Review 9.  Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases.

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10.  Investigations into the Antibacterial Mechanism of Action of Viridicatumtoxins.

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Journal:  ACS Infect Dis       Date:  2020-06-04       Impact factor: 5.578

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