Literature DB >> 23892747

Rhodococcus jostii porin A (RjpA) functions in cholate uptake.

Vijayakumar Somalinga1, William W Mohn.   

Abstract

RjpA in Rhodococcus jostii is the ortholog of a channel-forming porin, MspA. Deletion of rjpA delayed growth of R. jostii on cholate but not on cholesterol. Eventual growth on cholate involved increased expression of other porins, namely, RjpB, RjpC, and RjpD. Porins appear essential for the uptake of bile acids by mycolic acid bacteria.

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Year:  2013        PMID: 23892747      PMCID: PMC3811372          DOI: 10.1128/AEM.01242-13

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  23 in total

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