Literature DB >> 23890411

Anterior cervical discectomy plus intervertebral polyetheretherketone cage fusion over three and four levels without plating is safe and effective long-term.

Erlick A C Pereira1, Aswin Chari, Jonathan Hempenstall, John C D Leach, Hari Chandran, Tom A D Cadoux-Hudson.   

Abstract

Anterior cervical discectomy and fusion (ACDF) is an established treatment for single-level cervical spondylotic myelopathy and radiculopathy, yet its stand-alone use for multi-level disease of the subaxial cervical spine remains controversial. We report a prospectively studied case series of 30 patients receiving polyetheretherketone (PEEK) cage fusion over three and four cervical levels without anterior plating. Seven (23.3%) four-level procedures (all C3 to C7) were performed, the other 23 (76.7%) being three-level, with 19 (64.4%) at C4 to C7 and four (12.3%) at C3 to C6. Long-term follow-up of more than 2 years was available in 67% of patients. This cohort showed statistically significant improvements in visual analogue score for neck pain (p=0.0006), arm pain (p=0.0003) and Japanese Orthopaedic Association myelopathy score (p=0.002). Fused segment heights increased by 0.6-1.1%. Adjacent segment disease requiring ACDF at C3-4 was seen in 6.7% of patients (one after trauma) at a mean follow-up of 62 months. Same segment recurrence requiring posterior decompression with instrumented fusion was found in 10% of patients at a mean follow-up of 49 months, only one of whom had radiological evidence of cage subsidence. The results suggest the procedure is safe and effective with potentially less morbidity than anterior plating, shorter inpatient stays than posterior approaches, acceptable same segment recurrence and lower than predicted adjacent segment disease rates. Crown
Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  ACDF; Adjacent segment disease; Anterior cervical discectomy and fusion; Complications; Long-term follow-up; Multi-level; PEEK

Mesh:

Substances:

Year:  2013        PMID: 23890411     DOI: 10.1016/j.jocn.2012.10.028

Source DB:  PubMed          Journal:  J Clin Neurosci        ISSN: 0967-5868            Impact factor:   1.961


  13 in total

1.  Single level anterior cervical discectomy and interbody fusion.

Authors:  Cesare Faldini; Mohammadreza Chehrassan; Fabrizio Perna; Raffaele Borghi; Antonio Mazzotti; Francesco Traina
Journal:  Eur Spine J       Date:  2017-09       Impact factor: 3.134

2.  Using the modified Delphi method to establish a new Chinese clinical consensus of the treatments for cervical radiculopathy.

Authors:  Lei Zang; Ning Fan; Yong Hai; S B Lu; Q J Su; J C Yang; Peng Du; Y J Gao
Journal:  Eur Spine J       Date:  2015-03-10       Impact factor: 3.134

3.  Clinical and radiological outcomes following hybrid surgery in the treatment of multi-level cervical spondylosis: over a 2-year follow-up.

Authors:  Ji-Sheng Shi; Bin Lin; Chao Xue; Hai-Shen Zhang; Zhi-Da Chen; Zhong-Sheng Zhao
Journal:  J Orthop Surg Res       Date:  2015-12-16       Impact factor: 2.359

4.  Outcomes Evaluation of Zero-Profile Devices Compared to Stand-Alone PEEK Cages for the Treatment of Three- and Four-Level Cervical Disc Disease.

Authors:  Peter C Gerszten; Erin Paschel; Hazem Mashaly; Hatem Sabry; Hasan Jalalod'din; Khaled Saoud
Journal:  Cureus       Date:  2016-09-10

Review 5.  Prevalence of adjacent segment disease following cervical spine surgery: A PRISMA-compliant systematic review and meta-analysis.

Authors:  Lingde Kong; Junming Cao; Linfeng Wang; Yong Shen
Journal:  Medicine (Baltimore)       Date:  2016-07       Impact factor: 1.889

6.  A Prospective Study with Cage-Only or Cage-with-Plate Fixation in Anterior Cervical Discectomy and Interbody Fusion of One and Two Levels.

Authors:  Sam Yeol Kim; Seung Hwan Yoon; Dokeun Kim; Chang Hyun Oh; Seyang Oh
Journal:  J Korean Neurosurg Soc       Date:  2017-10-25

7.  Incidence and clinical relevance of cage subsidence in anterior cervical discectomy and fusion: a systematic review.

Authors:  Iris Noordhoek; Marvyn T Koning; Wilco C H Jacobs; Carmen L A Vleggeert-Lankamp
Journal:  Acta Neurochir (Wien)       Date:  2018-02-21       Impact factor: 2.216

8.  Risk factors for subsidence in anterior cervical fusion with stand-alone polyetheretherketone (PEEK) cages: a review of 82 cases and 182 levels.

Authors:  Ting-Hsien Kao; Chen-Hao Wu; Yu-Ching Chou; Hsien-Te Chen; Wen-Hsien Chen; Hsi-Kai Tsou
Journal:  Arch Orthop Trauma Surg       Date:  2014-08-07       Impact factor: 3.067

9.  Long-Term Follow-Up Results of Anterior Cervical Inter-Body Fusion with Stand-Alone Cages.

Authors:  Woong-Beom Kim; Seung-Jae Hyun; Hoyong Choi; Ki-Jeong Kim; Tae-Ahn Jahng; Hyun-Jib Kim
Journal:  J Korean Neurosurg Soc       Date:  2016-07-08

10.  Anterior cervical discectomy and fusion with stand-alone anchored cages versus posterior laminectomy and fusion for four-level cervical spondylotic myelopathy: a retrospective study with 2-year follow-up.

Authors:  Bing Wang; Guohua Lü; Lei Kuang
Journal:  BMC Musculoskelet Disord       Date:  2018-07-12       Impact factor: 2.362

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