Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Application of cell encapsulation for controlled delivery of biological therapeutics.

Literature DB >> 23886766

Application of cell encapsulation for controlled delivery of biological therapeutics.

G Orive¹, E Santos², J L Pedraz², R M Hernández³.

Abstract

Cell microencapsulation technology is likely to have an increasingly important role in new approaches rather than the classical and pioneering organ replacement. Apart from becoming a tool for protein and morphogen release and long-term drug delivery, it is becoming a new three-dimensional platform for stem cell research. Recent progress in the field has resulted in biodegradable scaffolds that are able to retain and release the cell content in different anatomical locations. Additional advances include the use biomimetic scaffolds that provide greater control over material-cell interactions and the development of more precise encapsulated cell-tracking systems. This review summarises the state of the art of cell microencapsulation and discusses the main directions and challenges of this field towards the controlled delivery of biological therapeutics.

Keywords: Cell encapsulation; Drug delivery; Microcapsule; Protein release; Scaffold

Mesh：

Year: 2013 PMID： 23886766 DOI： 10.1016/j.addr.2013.07.009

Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470

Keyword Cloud
Cited

17 in total

Review 1. Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture.

Authors: Haishui Huang; Yin Yu; Yong Hu; Xiaoming He; O Berk Usta; Martin L Yarmush
Journal: Lab Chip Date: 2017-05-31 Impact factor: 6.799

2. Regulation of dendrimer/dextran material performance by altered tissue microenvironment in inflammation and neoplasia.

Authors: Nuria Oliva; Maria Carcole; Margarita Beckerman; Sivan Seliktar; Alison Hayward; James Stanley; Nicola Maria Anne Parry; Elazer R Edelman; Natalie Artzi
Journal: Sci Transl Med Date: 2015-01-28 Impact factor: 17.956

Review 3. Specialty Tough Hydrogels and Their Biomedical Applications.

Authors: Stephanie Fuchs; Kaavian Shariati; Minglin Ma
Journal: Adv Healthc Mater Date: 2019-12-17 Impact factor: 9.933

4. Identification of IL-1β and LPS as optimal activators of monolayer and alginate-encapsulated mesenchymal stromal cell immunomodulation using design of experiments and statistical methods.

Authors: Andrea Gray; Timothy Maguire; Rene Schloss; Martin L Yarmush
Journal: Biotechnol Prog Date: 2015-05-28

5. Reactive Oxygen Species Shielding Hydrogel for the Delivery of Adherent and Nonadherent Therapeutic Cell Types.

Authors: Bryan R Dollinger; Mukesh K Gupta; John R Martin; Craig L Duvall
Journal: Tissue Eng Part A Date: 2017-04-07 Impact factor: 3.845

6. Sizes and Sufficient Quantities of MSC Microspheres for Intrathecal Injection to Modulate Inflammation in Spinal Cord Injury.

Authors: Suneel Kumar; Joanne Babiarz; Sayantani Basak; Jae Hwan Kim; Jeffrey Barminko; Andrea Gray; Parry Mendapara; Rene Schloss; Martin L Yarmush; Martin Grumet
Journal: Nano Life Date: 2015-12

Application of cell encapsulation for controlled delivery of biological therapeutics.

Review 1. Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture.

2. Regulation of dendrimer/dextran material performance by altered tissue microenvironment in inflammation and neoplasia.

Review 3. Specialty Tough Hydrogels and Their Biomedical Applications.

4. Identification of IL-1β and LPS as optimal activators of monolayer and alginate-encapsulated mesenchymal stromal cell immunomodulation using design of experiments and statistical methods.

5. Reactive Oxygen Species Shielding Hydrogel for the Delivery of Adherent and Nonadherent Therapeutic Cell Types<sup/>.

6. Sizes and Sufficient Quantities of MSC Microspheres for Intrathecal Injection to Modulate Inflammation in Spinal Cord Injury.

7. Cell Microencapsulation and Cryopreservation with Low Molecular Weight Hyaluronan and Dimethyl Sulfoxide.

8. Microencapsulated equine mesenchymal stromal cells promote cutaneous wound healing in vitro.

9. Layer-by-layer paper-stacking nanofibrous membranes to deliver adipose-derived stem cells for bone regeneration.

Review 10. The Rise of CRISPR/Cas for Genome Editing in Stem Cells.