Literature DB >> 23885879

Microtubule motors: a new hope for kinesin-5 inhibitors?

Aaron Groen1.   

Abstract

A new study demonstrates that two microtubule plus end-directed kinesins can oppose each other. The cause of this apparent contradiction is the specific orientation of microtubules on which each motor exerts its force.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23885879     DOI: 10.1016/j.cub.2013.05.049

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  2 in total

Review 1.  Prime movers: the mechanochemistry of mitotic kinesins.

Authors:  Robert A Cross; Andrew McAinsh
Journal:  Nat Rev Mol Cell Biol       Date:  2014-04       Impact factor: 94.444

2.  The Kinesin-12 Kif15 is a processive track-switching tetramer.

Authors:  Hauke Drechsler; Toni McHugh; Martin R Singleton; Nicholas J Carter; Andrew D McAinsh
Journal:  Elife       Date:  2014-03-25       Impact factor: 8.140

  2 in total

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