Literature DB >> 23885166

Macular hole formation in a patient with Irvine-Gass syndrome: coincidence or rare complication?

Marilita M Moschos1, Zisis Gatzioufas, Tryfon Rotsos, Chrysanthos Symeonidis, Xuefei Song, Berthold Seitz.   

Abstract

BACKGROUND: Macular edema (ME) is caused by abnormal retinal capillary permeability and has also been described as a postoperative complication of cataract surgery (Irvine-Gass syndrome).
OBJECTIVE: To present a patient with Irvine-Gass syndrome in the right eye complicated with a macular hole (MH) in the same eye and possible associations between these two entities. CASE REPORT: A 72-year-old male with a history of uneventful bilateral cataract surgery was followed-up with biomicroscopy and optical coherence tomography (OCT). Four weeks after cataract surgery oculus dexter (OD), there was progressive visual deterioration (best corrected visual acuity [BCVA]: 0.5). OCT disclosed cystoid ME. A parabulbar triamcinolone injection, dexamethasone 0.1% and ketorolac 0.4% eye drops, both 4 times per day OD were administered. Six weeks later (BCVA OD: 0.2), OCT revealed cystoid ME and full-thickness MH.
CONCLUSION: ME secondary to diabetes or central retinal vein occlusion may lead to MH by inducing focal vitreomacular traction and by triggering inflammatory mechanisms which facilitate a marked thinning of the fovea. MH may occur even in cases of pseudophakic ME, representing a rare complication of Irvine-Gass syndrome.

Entities:  

Keywords:  Irvine-Gass syndrome; macular edema; macular hole

Year:  2013        PMID: 23885166      PMCID: PMC3716554          DOI: 10.2147/OPTH.S44200

Source DB:  PubMed          Journal:  Clin Ophthalmol        ISSN: 1177-5467


  6 in total

1.  Acute full-thickness macular hole after uncomplicated phacoemulsification cataract surgery.

Authors:  J A Patterson; E Ezra; Z J Gregor
Journal:  Am J Ophthalmol       Date:  2001-06       Impact factor: 5.258

2.  Macular hole genesis: the hydration theory.

Authors:  Paul E Tornambe
Journal:  Retina       Date:  2003-06       Impact factor: 4.256

3.  Idiopathic senile macular hole: its early stages and pathogenesis. 1988.

Authors:  J Donald M Gass
Journal:  Retina       Date:  2003-12       Impact factor: 4.256

4.  Lamellar macular hole formation in patients with diabetic cystoid macular edema.

Authors:  Noriyuki Unoki; Kazuaki Nishijima; Mihori Kita; Hideyasu Oh; Atsushi Sakamoto; Takanori Kameda; Hisako Hayashi; Nagahisa Yoshimura
Journal:  Retina       Date:  2009-09       Impact factor: 4.256

5.  Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema.

Authors:  Baruch D Kuppermann; Mark S Blumenkranz; Julia A Haller; George A Williams; David V Weinberg; Connie Chou; Scott M Whitcup
Journal:  Arch Ophthalmol       Date:  2007-03

6.  Retinal detachment due to a macular hole in a patient with Behcet disease treated with vitrectomy and silicone oil tamponade.

Authors:  I Georgalas; N Markomichelakis; I Ladas
Journal:  Eur J Ophthalmol       Date:  2008 Nov-Dec       Impact factor: 2.597

  6 in total
  1 in total

1.  Full thickness macular hole following intravitreal ranibizumab injection for diabetic macular edema; a rare complication or coincidence?

Authors:  Hasan Basri Arifoglu; Arzu Seyhan Karatepe Hashas; T Lay Ersekerci; Mustafa Atas
Journal:  Indian J Ophthalmol       Date:  2015-04       Impact factor: 1.848

  1 in total

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