Literature DB >> 23884449

Fe-promoted cross coupling of homobenzylic methyl ethers with Grignard reagents via sp3 C-O bond cleavage.

Shuang Luo1, Da-Gang Yu, Ru-Yi Zhu, Xin Wang, Lei Wang, Zhang-Jie Shi.   

Abstract

The first iron-catalyzed formal cross coupling of homobenzylic methyl ethers with alkyl Grignard reagents is realized. The reaction is proposed to proceed through a sequence of dehydroalkoxylation to form the vinyl-intermediate, followed by Fe-catalyzed selective carbometalation to form a benzylic Grignard reagent.

Entities:  

Year:  2013        PMID： 23884449     DOI： 10.1039/c3cc43616k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Activation of diverse carbon-heteroatom and carbon-carbon bonds via palladium(II)-catalysed β-X elimination.

Authors:  Van T Tran; John A Gurak; Kin S Yang; Keary M Engle
Journal:  Nat Chem       Date:  2018-08-20       Impact factor: 24.427

2.  LiCl-promoted amination of β-methoxy amides (γ-lactones).

Authors:  Ru Zhao; Bing-Lin Zeng; Wen-Qiang Jia; Hong-Yi Zhao; Long-Ying Shen; Xiao-Jian Wang; Xian-Dao Pan
Journal:  RSC Adv       Date:  2020-09-21       Impact factor: 4.036

3.  Practical carbon-carbon bond formation from olefins through nickel-catalyzed reductive olefin hydrocarbonation.

Authors:  Xi Lu; Bin Xiao; Zhenqi Zhang; Tianjun Gong; Wei Su; Jun Yi; Yao Fu; Lei Liu
Journal:  Nat Commun       Date:  2016-04-01       Impact factor: 14.919
  3 in total

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