Literature DB >> 23883924

Alzheimer's disease: From big data to mechanism.

Vivek Swarup, Daniel H Geschwind.   

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Year:  2013        PMID： 23883924      PMCID： PMC4409124          DOI： 10.1038/nature12457

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  10 in total

Review 1.  Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis.

Authors:  Scott A Small; Sam Gandy
Journal:  Neuron       Date:  2006-10-05       Impact factor: 17.173

2.  Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.

Authors:  Bin Zhang; Chris Gaiteri; Liviu-Gabriel Bodea; Zhi Wang; Joshua McElwee; Alexei A Podtelezhnikov; Chunsheng Zhang; Tao Xie; Linh Tran; Radu Dobrin; Eugene Fluder; Bruce Clurman; Stacey Melquist; Manikandan Narayanan; Christine Suver; Hardik Shah; Milind Mahajan; Tammy Gillis; Jayalakshmi Mysore; Marcy E MacDonald; John R Lamb; David A Bennett; Cliona Molony; David J Stone; Vilmundur Gudnason; Amanda J Myers; Eric E Schadt; Harald Neumann; Jun Zhu; Valur Emilsson
Journal:  Cell       Date:  2013-04-25       Impact factor: 41.582

3.  Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice.

Authors:  S Sakura Minami; Thomas G Clifford; Hyang-Sook Hoe; Yasuji Matsuoka; G William Rebeck
Journal:  Neurobiol Aging       Date:  2011-07-07       Impact factor: 4.673

Review 4.  Genetic insights in Alzheimer's disease.

Authors:  Karolien Bettens; Kristel Sleegers; Christine Van Broeckhoven
Journal:  Lancet Neurol       Date:  2013-01       Impact factor: 44.182

5.  Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease.

Authors:  Herve Rhinn; Ryousuke Fujita; Liang Qiang; Rong Cheng; Joseph H Lee; Asa Abeliovich
Journal:  Nature       Date:  2013-07-24       Impact factor: 49.962

6.  The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease.

Authors:  Yasuo Ihara; Maho Morishima-Kawashima; Ralph Nixon
Journal:  Cold Spring Harb Perspect Med       Date:  2012-08-01       Impact factor: 6.915

Review 7.  Neuroscience in the era of functional genomics and systems biology.

Authors:  Daniel H Geschwind; Genevieve Konopka
Journal:  Nature       Date:  2009-10-15       Impact factor: 49.962

8.  A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging.

Authors:  Jeremy A Miller; Michael C Oldham; Daniel H Geschwind
Journal:  J Neurosci       Date:  2008-02-06       Impact factor: 6.167

9.  Transcriptomic analysis of autistic brain reveals convergent molecular pathology.

Authors:  Irina Voineagu; Xinchen Wang; Patrick Johnston; Jennifer K Lowe; Yuan Tian; Steve Horvath; Jonathan Mill; Rita M Cantor; Benjamin J Blencowe; Daniel H Geschwind
Journal:  Nature       Date:  2011-05-25       Impact factor: 49.962

10.  Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.

Authors:  Ellen M Wijsman; Nathan D Pankratz; Yoonha Choi; Joseph H Rothstein; Kelley M Faber; Rong Cheng; Joseph H Lee; Thomas D Bird; David A Bennett; Ramon Diaz-Arrastia; Alison M Goate; Martin Farlow; Bernardino Ghetti; Robert A Sweet; Tatiana M Foroud; Richard Mayeux
Journal:  PLoS Genet       Date:  2011-02-17       Impact factor: 5.917
  10 in total
  9 in total

Review 1.  Analytical tools and current challenges in the modern era of neuroepigenomics.

Authors:  Ian Maze; Li Shen; Bin Zhang; Benjamin A Garcia; Ningyi Shao; Amanda Mitchell; HaoSheng Sun; Schahram Akbarian; C David Allis; Eric J Nestler
Journal:  Nat Neurosci       Date:  2014-10-28       Impact factor: 24.884

Review 2.  Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling.

Authors:  Linlin Zhao; Heather L Ciallella; Lauren M Aleksunes; Hao Zhu
Journal:  Drug Discov Today       Date:  2020-07-11       Impact factor: 7.851

Review 3.  Big Data and Artificial Intelligence Modeling for Drug Discovery.

Authors:  Hao Zhu
Journal:  Annu Rev Pharmacol Toxicol       Date:  2019-09-13       Impact factor: 13.820

Review 4.  Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease.

Authors:  Cassia R Overk; Eliezer Masliah
Journal:  Biochem Pharmacol       Date:  2014-01-21       Impact factor: 5.858

5.  Big Data and Dementia: Charting the Route Ahead for Research, Ethics, and Policy.

Authors:  Marcello Ienca; Effy Vayena; Alessandro Blasimme
Journal:  Front Med (Lausanne)       Date:  2018-02-06

Review 6.  Role of brain imaging in disorders of brain-gut interaction: a Rome Working Team Report.

Authors:  Emeran A Mayer; Jennifer Labus; Qasim Aziz; Irene Tracey; Lisa Kilpatrick; Sigrid Elsenbruch; Petra Schweinhardt; Lukas Van Oudenhove; David Borsook
Journal:  Gut       Date:  2019-06-07       Impact factor: 23.059

Review 7.  Data integration in the era of omics: current and future challenges.

Authors:  David Gomez-Cabrero; Imad Abugessaisa; Dieter Maier; Andrew Teschendorff; Matthias Merkenschlager; Andreas Gisel; Esteban Ballestar; Erik Bongcam-Rudloff; Ana Conesa; Jesper Tegnér
Journal:  BMC Syst Biol       Date:  2014-03-13

8.  The Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer's Disease: Implications for Treatment.

Authors:  Yanyan Kong; Lin Huang; Weihao Li; Xuanting Liu; Yinping Zhou; Cuiping Liu; Shibo Zhang; Fang Xie; Zhengwei Zhang; Donglang Jiang; Weiyan Zhou; Ruiqing Ni; Chencheng Zhang; Bomin Sun; Jiao Wang; Yihui Guan
Journal:  Front Cell Dev Biol       Date:  2021-07-01

Review 9.  Big data in chemical toxicity research: the use of high-throughput screening assays to identify potential toxicants.

Authors:  Hao Zhu; Jun Zhang; Marlene T Kim; Abena Boison; Alexander Sedykh; Kimberlee Moran
Journal:  Chem Res Toxicol       Date:  2014-09-16       Impact factor: 3.739
  9 in total

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