Literature DB >> 23883464

[Overweight, obesity, diabetes, and hypertension in endometrial cancer].

Tania L N Sanz-Chávez1, Diana Vilar-Compte, Luigina de Nicola-Delfín, Abelardo Meneses-García.   

Abstract

BACKGROUND: in postmenopausal women, the excess of fat has been associated with an increased risk of endometrial cancer. The aim of the study was to determine the prevalence of overweight, obesity, diabetes and hypertension in patients with endometrial cancer.
METHODS: we collected demographic, clinical, laboratory and histopathological information from the electronic records of patients diagnosed with endometrial cancer in the period from January 2009 to July 2011. Subsequently descriptive analysis of the information was done.
RESULTS: a total of 274 records. The average age of patients was 54 years. The 50.4 % were postmenopausal. At the time of diagnosis, 112 cases (48.6 %) were in clinical stage I. Of all patients, 104 (37.9 %) had diabetes mellitus, 122 (44.5 %) hypertension, 194 (72.6 %) were overweight or obese, and 24 cases were registered with the metabolic syndrome.
CONCLUSIONS: in regards to this diagnosis the results show a higher incidence of overweight and obesity compared with other countries. It is necessary to conduct further studies to assess the relationship of excess fat as a risk factor for endometrial cancer.

Entities:  

Keywords:  diabetes mellitus; endometrial neoplasms; hypertension; obesity; risk factors

Mesh:

Year:  2013        PMID: 23883464

Source DB:  PubMed          Journal:  Rev Med Inst Mex Seguro Soc        ISSN: 0443-5117


  3 in total

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Authors:  Sayed Hossain Davoodi; Talieh Malek-Shahabi; Ali Malekshahi-Moghadam; Roghieh Shahbazi; Saeideh Esmaeili
Journal:  Iran J Cancer Prev       Date:  2013

2.  Association of abnormal glucose metabolism and insulin resistance in patients with atypical and typical endometrial cancer.

Authors:  Yongjing Lai; Chuanying Sun
Journal:  Oncol Lett       Date:  2017-12-12       Impact factor: 2.967

3.  B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers.

Authors:  Ji-Shui Wang; Fang Ruan; Li-Zhu Guo; Feng-Ge Wang; Fu-Ling Wang; Hong-Min An
Journal:  Genes Genomics       Date:  2021-03-08       Impact factor: 1.839

  3 in total

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