| Literature DB >> 2388328 |
S A Berger1, H Yavetz, G Paz, A Gorea, Z Homonnai.
Abstract
A single oral dose of ofloxacin (400 mg.) or ciprofloxacin (500 mg.) was administered to each of 40 men. The mean concentrations of ofloxacin in semen exceeded those of ciprofloxacin at 1 hour (p = 0.035) and 24 hours (p = 0.028), while the levels of the 2 drugs at 2 and 4 hours were comparable. Semen concentrations of ofloxacin but not ciprofloxacin exceeded the reported minimal inhibitory concentration of Enterobacteriaceae, Chlamydia trachomatis and genital Mycoplasma species 24 hours after dosage.Entities:
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Year: 1990 PMID: 2388328 DOI: 10.1016/s0022-5347(17)39554-x
Source DB: PubMed Journal: J Urol ISSN: 0022-5347 Impact factor: 7.450