Literature DB >> 23882108

The effect of a mechanical ventilation discontinuation protocol in patients with simple and difficult weaning: impact on clinical outcomes.

Pooja Gupta1, Katherine Giehler, Ryan W Walters, Katherine Meyerink, Ariel M Modrykamien.   

Abstract

OBJECTIVE: We sought to determine whether the utilization of a respiratory therapist (RT) driven mechanical ventilation weaning protocol is associated with improvement in clinical outcomes in subjects with simple versus difficult weaning.
METHODS: This was a retrospective analysis of prospectively collected data obtained during a quality improvement project. We collected data on 803 consecutive mechanically ventilated patients admitted to the ICU of an academic tertiary care hospital. We compared an RT-driven weaning protocol to a physician-driven weaning strategy.
RESULTS: Of the 803 patients, 651 with simple weaning and 131 with difficult weaning were included in the analysis. In the subjects with simple weaning, 514 (79%) were weaned with the RT-driven protocol. Among the difficult weaning subjects, 101(77.1%) were liberated with the RT-driven protocol. A multivariate analysis, which included Acute Physiology and Chronic Health Evaluation II, body mass index, and type of primary ICU team under which the subjects were admitted, revealed a significant difference in ventilator-free days at 28-days, which supports the RT-driven protocol over the physician-driven strategy. Specifically, the RT-driven protocol increased ventilator-free days by 20.92% and 68.2% among subjects with simple and difficult weaning, respectively. A multivariate analysis of ICU mortality and extubation failure found no significant difference between the RT-driven protocol and the physician-driven strategy.
CONCLUSIONS: The RT-driven weaning protocol increased ventilator-free days among subjects with simple and difficult weaning, with no significant differences in ICU mortality or extubation failure.

Entities:  

Keywords:  extubation; mechanical ventilation; protocols; respiratory failure; respiratory therapist; weaning

Mesh:

Year:  2013        PMID: 23882108     DOI: 10.4187/respcare.02558

Source DB:  PubMed          Journal:  Respir Care        ISSN: 0020-1324            Impact factor:   2.258


  3 in total

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Authors:  Joshua S Pearl; Ognjen Gajic; Yue Dong; Vitaly Herasevich; Michelle N Gong
Journal:  Ann Am Thorac Soc       Date:  2016-06

2.  An Artificial Neural Network Model for Predicting Successful Extubation in Intensive Care Units.

Authors:  Meng-Hsuen Hsieh; Meng-Ju Hsieh; Chin-Ming Chen; Chia-Chang Hsieh; Chien-Ming Chao; Chih-Cheng Lai
Journal:  J Clin Med       Date:  2018-08-25       Impact factor: 4.241

3.  Reduction of ventilatory time using the multidisciplinary disconnection protocol. Pilot study.

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Journal:  Rev Lat Am Enfermagem       Date:  2019-12-05
  3 in total

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