Literature DB >> 23881163

Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels.

Na Sun1, Axel Walch.   

Abstract

Mass spectrometry imaging (MSI) is a rapidly evolving technology that yields qualitative and quantitative distribution maps of small pharmaceutical-active molecules and their metabolites in tissue sections in situ. The simplicity, high sensitivity and ability to provide comprehensive spatial distribution maps of different classes of biomolecules make MSI a valuable tool to complement histopathology for diagnostics and biomarker discovery. In this review, qualitative and quantitative MSI of drugs and metabolites in tissue at therapeutic levels are discussed and the impact of this technique in drug discovery and clinical research is highlighted.

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Year:  2013        PMID： 23881163     DOI： 10.1007/s00418-013-1127-4

Source DB:  PubMed          Journal:  Histochem Cell Biol        ISSN： 0948-6143            Impact factor:   4.304


  54 in total

1.  On the nature of the chemical noise in MALDI mass spectra.

Authors:  Andrew N Krutchinsky; Brian T Chait
Journal:  J Am Soc Mass Spectrom       Date:  2002-02       Impact factor: 3.109

2.  Mass spectrometry imaging with high resolution in mass and space (HR(2) MSI) for reliable investigation of drug compound distributions on the cellular level.

Authors:  Andreas Römpp; Sabine Guenther; Zoltan Takats; Bernhard Spengler
Journal:  Anal Bioanal Chem       Date:  2011-04-26       Impact factor: 4.142

3.  Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry.

Authors:  Michelle L Reyzer; Yunsheng Hsieh; Kwokei Ng; Walter A Korfmacher; Richard M Caprioli
Journal:  J Mass Spectrom       Date:  2003-10       Impact factor: 1.982

4.  Sublimation as a method of matrix application for mass spectrometric imaging.

Authors:  Joseph A Hankin; Robert M Barkley; Robert C Murphy
Journal:  J Am Soc Mass Spectrom       Date:  2007-06-30       Impact factor: 3.109

5.  Determination of cucumarioside A₂-2 in mouse spleen by radiospectroscopy, MALDI-MS and MALDI-IMS.

Authors:  E A Pislyagin; P S Dmitrenok; T Yu Gorpenchenko; S A Avilov; A S Silchenko; D L Aminin
Journal:  Eur J Pharm Sci       Date:  2013-05-30       Impact factor: 4.384

6.  Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard.

Authors:  David A Pirman; Richard F Reich; András Kiss; Ron M A Heeren; Richard A Yost
Journal:  Anal Chem       Date:  2012-12-24       Impact factor: 6.986

7.  Evaluation of an accurate mass approach for the simultaneous detection of drug and metabolite distributions via whole-body mass spectrometric imaging.

Authors:  Sheerin K Shahidi-Latham; Sucharita M Dutta; Maria C Prieto Conaway; Patrick J Rudewicz
Journal:  Anal Chem       Date:  2012-08-07       Impact factor: 6.986

8.  Vitamin E imaging and localization in the neuronal membrane.

Authors:  Eric B Monroe; John C Jurchen; Jinju Lee; Stanislav S Rubakhin; Jonathan V Sweedler
Journal:  J Am Chem Soc       Date:  2005-09-07       Impact factor: 15.419

9.  Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue.

Authors:  Yunsheng Hsieh; Roger Casale; Elaine Fukuda; Jiwen Chen; Ian Knemeyer; Julia Wingate; Richard Morrison; Walter Korfmacher
Journal:  Rapid Commun Mass Spectrom       Date:  2006       Impact factor: 2.419

10.  A new combination MALDI matrix for small molecule analysis: application to imaging mass spectrometry for drugs and metabolites.

Authors:  Selina Rahman Shanta; Tae Young Kim; Ji Hye Hong; Jeong Hwa Lee; Chan Young Shin; Kyun-Hwan Kim; Young Hwan Kim; Sang Kyung Kim; Kwang Pyo Kim
Journal:  Analyst       Date:  2012-12-21       Impact factor: 4.616
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  21 in total

Review 1.  MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice.

Authors:  Michaela Aichler; Axel Walch
Journal:  Lab Invest       Date:  2015-01-26       Impact factor: 5.662

Review 2.  Challenges and recent advances in mass spectrometric imaging of neurotransmitters.

Authors:  Erin Gemperline; Bingming Chen; Lingjun Li
Journal:  Bioanalysis       Date:  2014-02       Impact factor: 2.681

3.  Quantification of small molecule drugs in biological tissue sections by imaging mass spectrometry using surrogate tissue-based calibration standards.

Authors:  Nozomi Takai; Yukari Tanaka; Hideo Saji
Journal:  Mass Spectrom (Tokyo)       Date:  2014-02-01

4.  Quantitative mass spectrometry imaging of emtricitabine in cervical tissue model using infrared matrix-assisted laser desorption electrospray ionization.

Authors:  Mark T Bokhart; Elias Rosen; Corbin Thompson; Craig Sykes; Angela D M Kashuba; David C Muddiman
Journal:  Anal Bioanal Chem       Date:  2014-10-16       Impact factor: 4.142

Review 5.  Spatially resolved absolute quantitation in thin tissue by mass spectrometry.

Authors:  Vilmos Kertesz; John F Cahill
Journal:  Anal Bioanal Chem       Date:  2021-04       Impact factor: 4.142

6.  Dynamic Range Expansion by Gas-Phase Ion Fractionation and Enrichment for Imaging Mass Spectrometry.

Authors:  Boone M Prentice; Daniel J Ryan; Kerri J Grove; D Shannon Cornett; Richard M Caprioli; Jeffrey M Spraggins
Journal:  Anal Chem       Date:  2020-09-09       Impact factor: 6.986

Review 7.  The Histochem Cell Biol conspectus: the year 2013 in review.

Authors:  Douglas J Taatjes; Jürgen Roth
Journal:  Histochem Cell Biol       Date:  2014-03-09       Impact factor: 4.304

8.  Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling.

Authors:  Brendan Prideaux; Mariam S ElNaggar; Matthew Zimmerman; Justin M Wiseman; Xiaohua Li; Véronique Dartois
Journal:  Int J Mass Spectrom       Date:  2015-02-01       Impact factor: 1.986

Review 9.  Ambient Mass Spectrometry Imaging Using Direct Liquid Extraction Techniques.

Authors:  Julia Laskin; Ingela Lanekoff
Journal:  Anal Chem       Date:  2015-11-24       Impact factor: 6.986

10.  A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies.

Authors:  K Huber; M Aichler; N Sun; A Buck; Z Li; I E Fernandez; S M Hauck; H Zitzelsberger; O Eickelberg; K P Janssen; U Keller; A Walch
Journal:  Histochem Cell Biol       Date:  2014-05-14       Impact factor: 4.304
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