Literature DB >> 23880980

Acute hepatitis A in an elderly patient after care worker travel to high endemicity country.

Erlend T Aasheim1, Martin Seymour, Koye Balogun, Siew-Lin Ngui, Chris J Williams, Ananda Giri Shankar.   

Abstract

Hepatitis A virus (HAV) is considered one of the most important vaccine-preventable diseases in travelers. HAV spreads from person to person via the fecal-oral route and gives rise to an estimated 1.4 million cases worldwide each year. In developing countries with poor sanitary conditions people tend to be infected during childhood and have few symptoms, whereas in developed countries with good sanitary conditions fewer people develop immunity during childhood. This leads to susceptible populations of adults, who are also more prone to severe complications. Here we describe two confirmed cases of hepatitis A associated with a nursing home. The index case was a care worker who had recently traveled to a high-endemicity country, and the second case was a resident at the nursing home where the index case worked. Both cases had an identical genotype IIIA strain, consistent with a transmission event. Current policy does not include a requirement for hepatitis A vaccine in care workers who travel to high endemicity countries despite the fact that infected care workers can potentially spread the disease to elderly patients and other groups at risk of severe complications from HAV infection. We suggest that employers should consider hepatitis A vaccine upon employment; particularly in care workers who plan to visit areas where HAV is known to be endemic.

Entities:  

Keywords:  Hepatitis A; Hepatitis A vaccine; United Kingdom; international travel; recommendations; vaccine

Mesh:

Year:  2013        PMID: 23880980      PMCID: PMC3981859          DOI: 10.4161/hv.25719

Source DB:  PubMed          Journal:  Hum Vaccin Immunother        ISSN: 2164-5515            Impact factor:   3.452


  14 in total

1.  Immunity to hepatitis A in paediatric and nursery nurses.

Authors:  C J Poole; A T Shakespeare
Journal:  Occup Med (Lond)       Date:  1996-10       Impact factor: 1.611

2.  The evolving epidemiology of hepatitis a in the United States: incidence and molecular epidemiology from population-based surveillance, 2005-2007.

Authors:  R Monina Klevens; Jeremy T Miller; Kashif Iqbal; Ann Thomas; Elena M Rizzo; Heather Hanson; Kristin Sweet; Quyen Phan; Alicia Cronquist; Yury Khudyakov; Guo-liang Xia; Philip Spradling
Journal:  Arch Intern Med       Date:  2010-11-08

3.  Incidence of hepatitis A in Israel following universal immunization of toddlers.

Authors:  Ron Dagan; Alex Leventhal; Emilia Anis; Paul Slater; Yaffa Ashur; Daniel Shouval
Journal:  JAMA       Date:  2005-07-13       Impact factor: 56.272

Review 4.  Hepatitis A in the era of vaccination.

Authors:  Annemarie Wasley; Anthony Fiore; Beth P Bell
Journal:  Epidemiol Rev       Date:  2006-06-14       Impact factor: 6.222

5.  Hepatitis A virus infections in travelers, 1988-2004.

Authors:  Margot Mutsch; Virginie Masserey Spicher; Christoph Gut; Robert Steffen
Journal:  Clin Infect Dis       Date:  2006-01-11       Impact factor: 9.079

6.  Hepatitis A as an occupational hazard.

Authors:  F Hofmann; G Wehrle; H Berthold; D Köster
Journal:  Vaccine       Date:  1992       Impact factor: 3.641

7.  A population-based seroprevalence study of hepatitis A virus using oral fluid in England and Wales.

Authors:  M C Morris-Cunnington; W J Edmunds; E Miller; D W G Brown
Journal:  Am J Epidemiol       Date:  2004-04-15       Impact factor: 4.897

Review 8.  The risk of hepatitis A infection among healthcare workers: a review of reported outbreaks and sero-epidemiologic studies.

Authors:  G Chodick; S Ashkenazi; Y Lerman
Journal:  J Hosp Infect       Date:  2006-02-20       Impact factor: 3.926

Review 9.  Seroprevalence of hepatitis A infection in a low endemicity country: a systematic review.

Authors:  Ba' Pham; Bernard Duval; Gaston De Serres; Vladimir Gilca; Andrea C Tricco; Jan Ochnio; David W Scheifele
Journal:  BMC Infect Dis       Date:  2005-07-07       Impact factor: 3.090

10.  Increasing age--an important adverse prognostic factor in hepatitis A virus infection.

Authors:  A Forbes; R Williams
Journal:  J R Coll Physicians Lond       Date:  1988-10
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  3 in total

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Journal:  Gastroenterol Clin North Am       Date:  2020-03-29       Impact factor: 3.806

2.  Vaccination policies for healthcare personnel: Current challenges and future perspectives.

Authors:  Helena C Maltezou; George Dounias; Venerando Rapisarda; Caterina Ledda
Journal:  Vaccine X       Date:  2022-05-31

3.  Prevalence of hepatitis A in the capitals of the States of North, Southeast and South regions of Brazil: decrease in prevalence and some consequences.

Authors:  Leila M M B Pereira; Airton T Stein; Gerusa Maria Figueiredo; Gabriela Perdomo Coral; Ulisses R Montarroyos; Maria Regina Alves Cardoso; Maria Cynthia Braga; Regina Celia Moreira; Alex A Dos Santos; Ricardo Alencar Ximenes
Journal:  Rev Inst Med Trop Sao Paulo       Date:  2021-04-26       Impact factor: 1.846

  3 in total

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