OBJECTIVE: Studies report overlap between autism spectrum disorders and psychosis. This may indicate a relationship between the 2 disorders or an artificial overlap due to similarity of symptoms. The aim of this study was to investigate whether autism spectrum disorder and autistic traits predict psychotic experiences in early adolescence. METHOD: This study analyzes prospective data from a cohort. A dataset was analyzed of 5,359 cohort members who had provided data on autistic traits and/or a diagnosis of an autism spectrum disorder and psychotic experiences at age 12 years. RESULTS: A diagnosis of an autism spectrum disorder (odds ratio = 2.81, 95% confidence interval = 1.07, 7.34 p = .035) and childhood autistic traits (odds ratio = 1.15, 95% confidence interval = 1.05, 1.26 p = .0018) were associated with psychotic experiences after adjustment for confounders. CONCLUSIONS: These findings suggest a shared neurodevelopmental origin for autism and psychosis.
OBJECTIVE: Studies report overlap between autism spectrum disorders and psychosis. This may indicate a relationship between the 2 disorders or an artificial overlap due to similarity of symptoms. The aim of this study was to investigate whether autism spectrum disorder and autistic traits predict psychotic experiences in early adolescence. METHOD: This study analyzes prospective data from a cohort. A dataset was analyzed of 5,359 cohort members who had provided data on autistic traits and/or a diagnosis of an autism spectrum disorder and psychotic experiences at age 12 years. RESULTS: A diagnosis of an autism spectrum disorder (odds ratio = 2.81, 95% confidence interval = 1.07, 7.34 p = .035) and childhood autistic traits (odds ratio = 1.15, 95% confidence interval = 1.05, 1.26 p = .0018) were associated with psychotic experiences after adjustment for confounders. CONCLUSIONS: These findings suggest a shared neurodevelopmental origin for autism and psychosis.
Authors: Timothy P Rutkowski; Jason P Schroeder; Georgette M Gafford; Stephen T Warren; David Weinshenker; Tamara Caspary; Jennifer G Mulle Journal: J Neurosci Res Date: 2016-11-08 Impact factor: 4.164
Authors: Keely Cheslack-Postava; Auli Suominen; Elina Jokiranta; Venla Lehti; Ian W McKeague; Andre Sourander; Alan S Brown Journal: J Am Acad Child Adolesc Psychiatry Date: 2014-08-01 Impact factor: 8.829