Literature DB >> 23880349

Uterus transplantation from a deceased donor.

Omer Ozkan1, Munire Erman Akar, Okan Erdogan, Ozlenen Ozkan, Necmiye Hadimioglu.   

Abstract

OBJECTIVE: To demonstrate the technique for uterus retrieval and transplantation from a multiorgan donor.
DESIGN: Video presentation of our case report. The video uses animation to demonstrate the technique. Institutional Review Board (IRB) approval was obtained.
SETTING: University hospital. PATIENT(S): A 21-year-old woman with complete müllerian agenesis. INTERVENTION(S): Uterus allotransplantation has been performed from a deceased donor. MAIN OUTCOME MEASURE(S): Acquirement of cyclic menstrual function. RESULT(S): This video demonstrates the technique for uterus retrieval, perfusion, and transplantation. The recipient patient has been monitored regularly for vascular flow, immunosuppression, and infection control since the operation. CONCLUSION(S): Uterus transplantation requires extensive evaluation of the recipient and donor by an experienced multidisciplinary transplantation team both pre- and postoperatively. It has major risks related to surgery, immunosuppression, and pregnancy. Uterus transplantation might be considered promising only after the birth of a near-term healthy baby.
Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Uterus transplantation; deceased donor; uterine factor infertility

Mesh:

Year:  2013        PMID: 23880349     DOI: 10.1016/j.fertnstert.2013.06.041

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  7 in total

Review 1.  Uterus transplantation: From animal models through the first heart beating pregnancy to the first human live birth.

Authors:  Omer Ozkan; Nasuh Utku Dogan; Ozlenen Ozkan; Inanc Mendilcioglu; Selen Dogan; Batu Aydinuraz; Mehmet Simsek
Journal:  Womens Health (Lond)       Date:  2016-07

2.  Human Uterus Transplantation: Have We Opened a Pandora's Box?

Authors:  Gautam N Allahbadia
Journal:  J Obstet Gynaecol India       Date:  2015-02

3.  Uterus Transplant: Does It Have Legs?

Authors:  C V Hegde
Journal:  J Obstet Gynaecol India       Date:  2017-07-21

Review 4.  Uterus transplantation: state of the art in 2021.

Authors:  Elliott G Richards; Ruth M Farrell; Stephanie Ricci; Uma Perni; Cristiano Quintini; Andreas Tzakis; Tommaso Falcone
Journal:  J Assist Reprod Genet       Date:  2021-05-31       Impact factor: 3.357

Review 5.  Uterus transplantation: current progress and future prospects.

Authors:  Liza Johannesson; Stina Järvholm
Journal:  Int J Womens Health       Date:  2016-02-05

Review 6.  Uterus transplantation: Toward clinical application in Japan.

Authors:  Nobuhiko Suganuma; Ayako Hayashi; Iori Kisu; Kouji Banno; Hisako Hara; Makoto Mihara
Journal:  Reprod Med Biol       Date:  2017-08-06

7.  Application of detergents or high hydrostatic pressure as decellularization processes in uterine tissues and their subsequent effects on in vivo uterine regeneration in murine models.

Authors:  Erna G Santoso; Keita Yoshida; Yasushi Hirota; Masanori Aizawa; Osamu Yoshino; Akio Kishida; Yutaka Osuga; Shigeru Saito; Takashi Ushida; Katsuko S Furukawa
Journal:  PLoS One       Date:  2014-07-24       Impact factor: 3.240

  7 in total

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