Literature DB >> 23877141

Challenging the dogma: relationship between time to healing and formation of hypertrophic scars after burn injuries.

Sameena Hassan1, Gillian Reynolds, Julie Clarkson, Peter Brooks.   

Abstract

Hypertrophic scarring (HTS) is defined as a scar, which is raised above the skin level and remains within the confines of the original lesion. The authors hypothesize that small surface area burns can be left to heal beyond 21 days without an increase in the incidence of HTS formation, within the confines of a carefully selected patient population. The authors have documented the number of days to healing in all patients conservatively managed in their outpatient burns clinic. All patients who took longer than 21 days to heal receive a follow-up telephone call. A multivariate regression analysis is used to confirm significant factors that impede healing time. This study included 181 conservatively managed burns with a male:female ratio of 1.63:1 and average age of 24.7 ± 21.69 years (range, 1 month to 85 years). In total, 32 patients (18%) took more than 21 days to heal (range, 22-88 days), of which five patients presented with HTS (days to healing range, 23-47; one mixed depth and four deep dermal). One patient did not attend for follow-up, two patients settled with silicone gel alone whereas one settled with pressure garments. One patient is still being seen. The only significant factor in predicting time to healing in the ANOVA model in this study was depth of burn (P = .01; confidence interval, 1.18-6.07). Advances in wound care and better understanding of the physiological processes involved in healing may now enable the management of smaller burns with dressings, delaying the need for early surgical debridement and skin grafting in certain individuals.

Entities:  

Mesh:

Year:  2014        PMID: 23877141     DOI: 10.1097/BCR.0b013e31829b330a

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  5 in total

Review 1.  Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring.

Authors:  Meilang Xue; Christopher J Jackson
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-03-01       Impact factor: 4.730

2.  Nanomedicine-based strategies to improve treatment of cutaneous leishmaniasis.

Authors:  Nowsheen Goonoo; Marie Andrea Laetitia Huët; Itisha Chummun; Nancy Karuri; Kingsley Badu; Fanny Gimié; Jonas Bergrath; Margit Schulze; Mareike Müller; Archana Bhaw-Luximon
Journal:  R Soc Open Sci       Date:  2022-06-15       Impact factor: 3.653

3.  A prospective study of time to healing and hypertrophic scarring in paediatric burns: every day counts.

Authors:  Elizabeth Chipp; Lisa Charles; Clare Thomas; Kate Whiting; Naiem Moiemen; Yvonne Wilson
Journal:  Burns Trauma       Date:  2017-01-19

4.  Increased burn healing time is associated with higher Vancouver Scar Scale score.

Authors:  Vidya Finlay; Sally Burrows; Maddison Burmaz; Hussna Yawary; Johanna Lee; Dale W Edgar; Fiona M Wood
Journal:  Scars Burn Heal       Date:  2017-03-14

5.  Validity of thermography for measuring burn wound healing potential.

Authors:  Michelle E Carrière; Louise E M de Haas; Anouk Pijpe; Annebeth Meij-de Vries; Kim L M Gardien; Paul P M van Zuijlen; Mariëlle E H Jaspers
Journal:  Wound Repair Regen       Date:  2019-12-14       Impact factor: 3.617

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.