Sean M Bailey1, Karen D Hendricks-Munoz2, Pradeep Mally1. 1. Division of Neonatology, Department of Pediatrics, New York University School of Medicine, NYU Langone Medical Center/Bellevue Hospital, New York. 2. Division of Neonatal Medicine, Department of Pediatrics, Virginia Commonwealth University School of Medicine, Critical Care Hospital, Richmond, Virginia.
Abstract
OBJECTIVE: To determine cerebral regional tissue oxygen saturation (CrSO2), renal regional tissue oxygen saturation (RrSO2), and splanchnic regional tissue oxygen saturation (SrSO2) values in healthy term infants. STUDY DESIGN: Near-infrared spectroscopy was used to simultaneously measure CrSO2, RrSO2, and SrSO2 continuously for a 1-hour period on the first and second days of life. RESULTS: A total of 41 subjects were monitored out of which complete data were available for 38 subjects. Mean CrSO2 was 78.2 ± 7.9% on first day; 78.3 ± 6.1% on second day (p = 0.95). Mean RrSO2 was 92.1 ± 5.3% on first day; 88.9 ± 5.9% on second day (p < 0.01). Mean SrSO2 was 69.9 ± 12.1% on first day and 75.3 ± 12.4% on second day (p = 0.02). CONCLUSION: There appears to be consistency in rSO2 values in healthy newborns. CrSO2 was similar on both days. Differences observed in RrSO2 and SrSO2 between days may represent a shift in somatic blood flow distribution taking place during the first day of life. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
OBJECTIVE: To determine cerebral regional tissue oxygen saturation (CrSO2), renal regional tissue oxygen saturation (RrSO2), and splanchnic regional tissue oxygen saturation (SrSO2) values in healthy term infants. STUDY DESIGN: Near-infrared spectroscopy was used to simultaneously measure CrSO2, RrSO2, and SrSO2 continuously for a 1-hour period on the first and second days of life. RESULTS: A total of 41 subjects were monitored out of which complete data were available for 38 subjects. Mean CrSO2 was 78.2 ± 7.9% on first day; 78.3 ± 6.1% on second day (p = 0.95). Mean RrSO2 was 92.1 ± 5.3% on first day; 88.9 ± 5.9% on second day (p < 0.01). Mean SrSO2 was 69.9 ± 12.1% on first day and 75.3 ± 12.4% on second day (p = 0.02). CONCLUSION: There appears to be consistency in rSO2 values in healthy newborns. CrSO2 was similar on both days. Differences observed in RrSO2 and SrSO2 between days may represent a shift in somatic blood flow distribution taking place during the first day of life. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Authors: Matthew W Harer; Paige E Condit; Jennifer E Chuck; Michael R Lasarev; Valerie Y Chock Journal: Pediatr Res Date: 2022-03-30 Impact factor: 3.953
Authors: Nhu N Tran; Jodie K Votava-Smith; John C Wood; Ashok Panigrahy; Choo Phei Wee; Matthew Borzage; S Ram Kumar; Paula M Murray; Mary-Lynn Brecht; Lisa Paquette; Kenneth M Brady; Bradley S Peterson Journal: PLoS One Date: 2021-05-10 Impact factor: 3.240