Literature DB >> 23867878

Intravitreal ranibizumab in choroidal neovascularisation due to multifocal choroiditis and panuveitis syndrome.

Doukas Dardabounis1, Efstratios Alvanos, Zisis Gatzioufas, Georgios D Panos.   

Abstract

We report the use of intravitreal ranibizumab as initial and only treatment in a case of peripapillary choroidal neovascularisation (CNV) in a patient with multifocal choroiditis and panuveitis (MCP) syndrome. A 54-year-old woman presented with sudden reduced vision in the right eye of 2 weeks duration. A full ophthalmological examination was performed including biomicroscopy, fluorescein angiography and optical coherence tomography. A peripapillary choroidal neovascular membrane with subretinal haemorrhage extending to the fovea was revealed due to MCP syndrome. Three intravitreal injections of ranibizumab were performed with monthly intervals. There was clearance of the subretinal haemorrhage and reduction of the leakage after the first injection. The visual acuity improved to 20/20 in 3 months and remained stable at 2-year follow-up without angiographical leakage. Intravitreal injections of ranibizumab could be tried in cases of CNV due to MCP syndrome with very good response.

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Year:  2013        PMID: 23867878      PMCID: PMC3736297          DOI: 10.1136/bcr-2013-009572

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

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Review 2.  Vascular endothelial growth factor biology: clinical implications for ocular treatments.

Authors:  R B Bhisitkul
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3.  Multifocal choroiditis with panuveitis incidence of ocular complications and of loss of visual acuity.

Authors:  Jennifer E Thorne; Susan Wittenberg; Douglas A Jabs; George B Peters; Terry L Reed; Sanjay R Kedhar; James P Dunn
Journal:  Ophthalmology       Date:  2006-09-25       Impact factor: 12.079

4.  Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor.

Authors:  A Kvanta; P V Algvere; L Berglin; S Seregard
Journal:  Invest Ophthalmol Vis Sci       Date:  1996-08       Impact factor: 4.799

5.  Variable phenotypes in patients diagnosed with idiopathic multifocal choroiditis.

Authors:  Robert E MacLaren; Susan L Lightman
Journal:  Clin Exp Ophthalmol       Date:  2006-04       Impact factor: 4.207

6.  Photodynamic therapy for juxtafoveal choroidal neovascularization associated with multifocal choroiditis.

Authors:  Maurizio Battaglia Parodi; Pierluigi Iacono; Sonela Spasse; Giuseppe Ravalico
Journal:  Am J Ophthalmol       Date:  2006-01       Impact factor: 5.258

Review 7.  Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration.

Authors:  Eugene W M Ng; Anthony P Adamis
Journal:  Can J Ophthalmol       Date:  2005-06       Impact factor: 1.882

8.  Bevacizumab (avastin) and ranibizumab (lucentis) for choroidal neovascularization in multifocal choroiditis.

Authors:  Howard F Fine; Inna Zhitomirsky; K Bailey Freund; Gaetano R Barile; Belinda L Shirkey; C Michael Samson; Lawrence A Yannuzzi
Journal:  Retina       Date:  2009-01       Impact factor: 4.256

9.  Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syndrome.

Authors:  J Brown; J C Folk; C V Reddy; A E Kimura
Journal:  Ophthalmology       Date:  1996-07       Impact factor: 12.079

10.  Angiographic and optical coherence tomographic results of the MARINA study of ranibizumab in neovascular age-related macular degeneration.

Authors:  Peter K Kaiser; Barbara A Blodi; Howard Shapiro; Nisha R Acharya
Journal:  Ophthalmology       Date:  2007-07-12       Impact factor: 12.079

  10 in total
  4 in total

1.  An efficacy analysis of anti-vascular endothelial growth factor therapy for choroidal neovascularization secondary to multifocal choroiditis and comparison with wet age-related macular degeneration.

Authors:  Lei Feng; Jiang-Hua Hu; Jie Chen; Xin Xie
Journal:  J Zhejiang Univ Sci B       Date:  2018 Apr.       Impact factor: 3.066

2.  Resolution of vitreomacular traction following intravitreal ranibizumab in cases of ocular toxoplasmosis with choroidal neovascularization.

Authors:  Petros Petrou; Ilias Georgalas; Nikolaos Markomichelakis; Ioannis Vergados; Emanuela Gianakaki; Alexander Rouvas
Journal:  Ther Clin Risk Manag       Date:  2013-10-18       Impact factor: 2.423

Review 3.  Ranibizumab for the treatment of degenerative ocular conditions.

Authors:  Magdalini Triantafylla; Horace F Massa; Doukas Dardabounis; Zisis Gatzioufas; Vassilios Kozobolis; Konstantinos Ioannakis; Irfan Perente; Georgios D Panos
Journal:  Clin Ophthalmol       Date:  2014-06-24

4.  Anti-VEGF Agents for the Treatment of Pigment Epithelial Detachments Associated with Neovascular Age-related Macular Degeneration: An Evidence-based Approach.

Authors:  Georgios D Panos; Zisis Gatzioufas
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2015
  4 in total

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