Literature DB >> 2386492

Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1.

N D Perkins1, K H Orchard, M L Collins, D S Latchman, G H Goodwin.   

Abstract

The erythroid transcription factor erythroid factor-1 (EF1) plays a critical role in the transcription of erythroid-specific genes. Here we report the presence of a factor with the mobility and sequence-specific DNA-binding characteristics of EF1 at low abundance in a wide variety of non-erythroid cell types. This is the first report of an EF1-like activity in non-erythroid cells and indicates that this factor may play a role in the regulation of genes expressed in such cells.

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Year:  1990        PMID: 2386492      PMCID: PMC1131613          DOI: 10.1042/bj2690543

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  15 in total

1.  Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene.

Authors:  V Mignotte; L Wall; E deBoer; F Grosveld; P H Romeo
Journal:  Nucleic Acids Res       Date:  1989-01-11       Impact factor: 16.971

2.  GATAAG; a cis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression.

Authors:  M Plumb; J Frampton; H Wainwright; M Walker; K Macleod; G Goodwin; P Harrison
Journal:  Nucleic Acids Res       Date:  1989-01-11       Impact factor: 16.971

3.  Multiple GF-1 binding sites flank the erythroid specific transcription unit of the human carbonic anhydrase I gene.

Authors:  H J Brady; J C Sowden; M Edwards; N Lowe; P H Butterworth
Journal:  FEBS Lett       Date:  1989-11-06       Impact factor: 4.124

4.  The human beta-globin gene 3' enhancer contains multiple binding sites for an erythroid-specific protein.

Authors:  L Wall; E deBoer; F Grosveld
Journal:  Genes Dev       Date:  1988-09       Impact factor: 11.361

5.  Mutational analysis of the chicken beta-globin enhancer reveals two positive-acting domains.

Authors:  M Reitman; G Felsenfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

6.  An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

Authors:  T Evans; M Reitman; G Felsenfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

7.  The purification of an erythroid protein which binds to enhancer and promoter elements of haemoglobin genes.

Authors:  N D Perkins; R H Nicolas; M A Plumb; G H Goodwin
Journal:  Nucleic Acids Res       Date:  1989-02-25       Impact factor: 16.971

8.  Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells.

Authors:  S F Tsai; D I Martin; L I Zon; A D D'Andrea; G G Wong; S H Orkin
Journal:  Nature       Date:  1989-06-08       Impact factor: 49.962

9.  Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice.

Authors:  R R Behringer; R E Hammer; R L Brinster; R D Palmiter; T M Townes
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

10.  Detection of two tissue-specific DNA-binding proteins with affinity for sites in the mouse beta-globin intervening sequence 2.

Authors:  D L Galson; D E Housman
Journal:  Mol Cell Biol       Date:  1988-01       Impact factor: 4.272

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  2 in total

1.  Progressive inactivation of the expression of an erythroid transcriptional factor in GM- and G-CSF-dependent myeloid cell lines.

Authors:  S Crotta; S Nicolis; A Ronchi; S Ottolenghi; L Ruzzi; Y Shimada; A R Migliaccio; G Migliaccio
Journal:  Nucleic Acids Res       Date:  1990-12-11       Impact factor: 16.971

2.  An erythroid specific enhancer upstream to the gene encoding the cell-type specific transcription factor GATA-1.

Authors:  S Nicolis; C Bertini; A Ronchi; S Crotta; L Lanfranco; E Moroni; B Giglioni; S Ottolenghi
Journal:  Nucleic Acids Res       Date:  1991-10-11       Impact factor: 16.971

  2 in total

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