Literature DB >> 23864138

19F NMR: a valuable tool for studying biological events.

Han Chen1, Stéphane Viel, Fabio Ziarelli, Ling Peng.   

Abstract

With the spectacular advancement of NMR techniques and the flourishing of fluorine chemistry allowing the synthesis of various fluorinated molecules, (19)F NMR represents a compelling option for studying myriad biological events ranging from the structure and function of biomolecules, enzymatic mechanisms, and metabolic pathways, through to drug screening and discovery as well as medical imaging. In this tutorial review, we aim to provide readers with a brief overview of the recent applications of (19)F NMR in various areas relating to biological and biomedical research, together with a brief introduction of specific hardware improvements permitting the practical implementation of (19)F NMR.

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Year:  2013        PMID: 23864138     DOI: 10.1039/c3cs60129c

Source DB:  PubMed          Journal:  Chem Soc Rev        ISSN: 0306-0012            Impact factor:   54.564


  49 in total

1.  Molecular characterization of the boron adducts of the proteasome inhibitor bortezomib with epigallocatechin-3-gallate and related polyphenols.

Authors:  Stephen J Glynn; Kevin J Gaffney; Marcos A Sainz; Stan G Louie; Nicos A Petasis
Journal:  Org Biomol Chem       Date:  2015-04-07       Impact factor: 3.876

2.  mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.

Authors:  Anna M Rydzik; Marcin Warminski; Pawel J Sikorski; Marek R Baranowski; Sylwia Walczak; Joanna Kowalska; Joanna Zuberek; Maciej Lukaszewicz; Elzbieta Nowak; Timothy D W Claridge; Edward Darzynkiewicz; Marcin Nowotny; Jacek Jemielity
Journal:  Nucleic Acids Res       Date:  2017-09-06       Impact factor: 16.971

3.  Oriented samples: a tool for determining the membrane topology and the mechanism of action of cationic antimicrobial peptides by solid-state NMR.

Authors:  Matthieu Fillion; Michèle Auger
Journal:  Biophys Rev       Date:  2015-02-24

4.  13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1.

Authors:  Sherwin J Abraham; Ricky C Cheng; Thomas A Chew; Chandra M Khantwal; Corey W Liu; Shimei Gong; Robert K Nakamoto; Merritt Maduke
Journal:  J Biomol NMR       Date:  2015-01-29       Impact factor: 2.835

5.  Investigation of higher-order RNA G-quadruplex structures in vitro and in living cells by 19F NMR spectroscopy.

Authors:  Hong-Liang Bao; Yan Xu
Journal:  Nat Protoc       Date:  2018-03-08       Impact factor: 13.491

Review 6.  A molecular engineering toolbox for the structural biologist.

Authors:  Galia T Debelouchina; Tom W Muir
Journal:  Q Rev Biophys       Date:  2017-01       Impact factor: 5.318

7.  Cosolute and Crowding Effects on a Side-By-Side Protein Dimer.

Authors:  Alex J Guseman; Gary J Pielak
Journal:  Biochemistry       Date:  2017-02-09       Impact factor: 3.162

8.  Perfluoro-tert-butyl Homoserine Is a Helix-Promoting, Highly Fluorinated, NMR-Sensitive Aliphatic Amino Acid: Detection of the Estrogen Receptor·Coactivator Protein-Protein Interaction by 19F NMR.

Authors:  Caitlin M Tressler; Neal J Zondlo
Journal:  Biochemistry       Date:  2017-02-15       Impact factor: 3.162

9.  Ultrahigh (19)F Loaded Cu1.75S Nanoprobes for Simultaneous (19)F Magnetic Resonance Imaging and Photothermal Therapy.

Authors:  Hongli Chen; Manli Song; Juan Tang; Gaofei Hu; Suying Xu; Zhide Guo; Nannan Li; Jiabin Cui; Xianzhong Zhang; Xiaoyuan Chen; Leyu Wang
Journal:  ACS Nano       Date:  2016-01-12       Impact factor: 15.881

Review 10.  Modern Approaches for Asymmetric Construction of Carbon-Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs.

Authors:  Yi Zhu; Jianlin Han; Jiandong Wang; Norio Shibata; Mikiko Sodeoka; Vadim A Soloshonok; Jaime A S Coelho; F Dean Toste
Journal:  Chem Rev       Date:  2018-04-02       Impact factor: 60.622

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