| Literature DB >> 2386376 |
T G Cantú1, J D Dick, D E Elliott, R L Humphrey, D M Kornhauser.
Abstract
Atypical vancomycin pharmacokinetics were observed in an immunoglobulin A myeloma patient. Drug concentrations in serum were extremely elevated, the elimination half-life was prolonged despite normal renal function, and the vancomycin therapy was ineffective. Extensive binding of vancomycin, presumably by high concentrations of an aberrant immunoglobulin A protein, may have accounted for these observations.Entities:
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Year: 1990 PMID: 2386376 PMCID: PMC176003 DOI: 10.1128/AAC.34.7.1459
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191