Literature DB >> 23863198

Non-canonical activity of retinoic acid in epigenetic control of embryonic stem cell.

Li-Na Wei1.   

Abstract

Non-canonical cytoplasmic activities and signal transduction of retinoic acid (RA) expand RA's pleiotropic effects in coordinating the epigenome in embryonic stem cell (ESC). Examples include RA-bound cellular retinoic acid binding protein I, which activates ERK2. By engaging both cytosolic and nuclear mediators, RA can efficiently augment ESC's epigenome.

Entities:  

Keywords:  CRABPI; ERK; OCT4; TR2; embryonic stem cell; epigenetic; retinoic acid

Mesh:

Substances:

Year:  2013        PMID: 23863198      PMCID: PMC3977914          DOI: 10.4161/trns.25395

Source DB:  PubMed          Journal:  Transcription        ISSN: 2154-1272


  31 in total

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