Literature DB >> 23860755

Population-based assessment of prevalence and risk factors for pterygium in the South Indian state of Andhra Pradesh: the Andhra Pradesh Eye Disease Study.

Srinivas Marmamula1, Rohit C Khanna, Gullapalli N Rao.   

Abstract

PURPOSE: To describe the prevalence and risk factors for pterygium in a population-based sample of individuals aged 30 years and older in South Indian state of Andhra Pradesh.
METHODS: A cross-sectional study was conducted in one urban and three rural locations in which 10,293 subjects were examined. All the subjects underwent comprehensive eye examination and a detailed interview by trained professionals. Pterygium was defined as fleshy fibro vascular growth, crossing the limbus, and typically seen on the nasal conjunctiva in either eye.
RESULTS: Data were analyzed for 5586 subjects who were aged 30 years and older at the time of participation. The mean age of the participants was 47.5 years (SD 13 years; range 30-102 years). In total, 46.4% were male, 56.7% had no education, 52.2% of them were involved in outdoor occupations, and 25% belonged to urban area. The prevalence of pterygium was 11.7% (95% confidence interval [CI]: 10.9-12.6). The multiple logistic regression analysis revealed significantly higher odds of pterygium among older age groups, rural residents (odds ratio [OR]: 1.8; 95% CI: 1.4-2.4; P > 0.01), and those involved in outdoor occupations (OR: 1.8; 95% CI: 1.5-2.2, P < 0.001). Education had a protective effect (OR: 0.6; 95% CI: 0.5-0.7; P < 0.001).
CONCLUSIONS: Pterygium is common in the South Indian state of Andhra Pradesh. Exposure to sunlight is a significant modifiable risk factor. Protecting the eyes from sunlight may decrease the risk of pterygium. However, the important public health challenge is to encourage the use of this protection as a routine in developing countries such as India.

Entities:  

Keywords:  Andhra Pradesh; India; outdoor occupations; pterygium; risk factors

Mesh:

Year:  2013        PMID: 23860755     DOI: 10.1167/iovs.13-12529

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


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