| Literature DB >> 23860639 |
Anil Kumar1,2, Fei Chen1,2, Anbu Mozhi1,2, Xu Zhang1, Yuanyuan Zhao1, Xiangdong Xue1,2, Yanli Hao3, Xiaoning Zhang3, Paul C Wang4, Xing-Jie Liang1.
Abstract
The advent of nanotechnology has reignited interest in the field of pharmaceutical science for the development of nanomedicine. Nanomedicinal formulations are nanometer-sized carrier materials designed for increasing the drug tissue bioavailability, thereby improving the treatment of systemically applied chemotherapeutic drugs. Nanomedicine is a new approach to deliver the pharmaceuticals through different routes of administration with safer and more effective therapies compared to conventional methods. To date, various kinds of nanomaterials have been developed over the years to make delivery systems more effective for the treatment of various diseases. Even though nanomaterials have significant advantages due to their unique nanoscale properties, there are still significant challenges in the improvement and development of nanoformulations with composites and other materials. Here in this review, we highlight the nanomedicinal formulations aiming to improve the balance between the efficacy and the toxicity of therapeutic interventions through different routes of administration and how to design nanomedicine for safer and more effective ways to improve the treatment quality. We also emphasize the environmental and health prospects of nanomaterials for human health care.Entities:
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Year: 2013 PMID： 23860639 PMCID： PMC3934102 DOI： 10.1039/c3nr01525d
Source DB: PubMed Journal: Nanoscale ISSN： 2040-3364 Impact factor: 7.790