Literature DB >> 23857615

Effects of early spasticity treatment on children with hemiplegic cerebral palsy: a preliminary study.

Marise Bueno Zonta1, Isac Bruck, Marilene Puppi, Sandra Muzzolon, Arnolfo de Carvalho Neto, Lúcia Helena Coutinho dos Santos.   

Abstract

OBJECTIVE: To compare motor and functional performance of two groups of children with hemiplegic cerebral palsy (HCP). Only the study group (SG) received early treatment of spasticity with botulinum neurotoxin type A (BXT-A).
METHODS: Gross Motor Function Measure (GMFM), functional performance (Pediatric Evaluation of Disability Inventory - PEDI), range of movement, gait pattern (Physician Rating Scale - PRS) and the speed of hand movements were considered.
RESULTS: The SG, composed of 11 HCP (45.64±6.3 months), was assessed in relation to the comparison group, composed of 13 HCP (45.92±6.4 months). SG showed higher scores in four of the five GMFM dimensions, which included scores that were statistically significant for dimension B, and higher scores in five of the six areas evaluated in the PEDI. Active wrist extension, the speed of hand movements and PRS score were higher in the SG.
CONCLUSION: Children who received early BXT-A treatment for spasticity showed higher scores in motor and functional performance.

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Year:  2013        PMID: 23857615     DOI: 10.1590/0004-282X20130061

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  4 in total

1.  [Effect of botulinum toxin A injection in the treatment of gastrocnemius spasticity in children aged 9-36 months with cerebral palsy: a prospective study].

Authors:  Deng-Na Zhu; Ming-Mei Wang; Jun Wang; Wei Zhang; He-Zhou Li; Po Yang; Hua-Chun Xiong; Guo-Hui Niu; San-Song Li; Yun-Xia Zhao
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2016-02

Review 2.  Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy.

Authors:  Francesco C Blumetti; João Carlos Belloti; Marcel Js Tamaoki; José A Pinto
Journal:  Cochrane Database Syst Rev       Date:  2019-10-08

3.  Age specificity in general and rehabilitation medical services in children with cerebral palsy.

Authors:  Dong-A Kim; Hyun-Sook Hong; Hee-Yeon Lee; Hye-Sun Lee; Min-Sung Kang
Journal:  Ann Rehabil Med       Date:  2014-12-24

4.  Early Fesoterodine Fumarate Administration Prevents Neurogenic Detrusor Overactivity in a Spinal Cord Transected Rat Model.

Authors:  Xavier Biardeau; Mikolaj Przydacz; Shachar Aharony; George Loutochin; Lysanne Campeau; Maeva Kyheng; Jacques Corcos
Journal:  PLoS One       Date:  2017-01-06       Impact factor: 3.240

  4 in total

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