Literature DB >> 23856817

Immunotherapy: Modified proinsulin to treat T1DM.

Tim Geach.   

Abstract

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Year:  2013        PMID： 23856817     DOI： 10.1038/nrendo.2013.133

Source DB:  PubMed          Journal:  Nat Rev Endocrinol        ISSN： 1759-5029            Impact factor:   43.330


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  1 in total

1.  Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.

Authors:  Bart O Roep; Nanette Solvason; Peter A Gottlieb; Joana R F Abreu; Leonard C Harrison; George S Eisenbarth; Liping Yu; Michael Leviten; William A Hagopian; John B Buse; Matthias von Herrath; Joanne Quan; Robert S King; William H Robinson; Paul J Utz; Hideki Garren; Lawrence Steinman
Journal:  Sci Transl Med       Date:  2013-06-26       Impact factor: 17.956
  1 in total

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