Literature DB >> 2385557

Rifampicin-induced upper gastrointestinal bleeding.

S A Zargar1, B R Thapa, A Sahni, S Mehta.   

Abstract

Gastrointestinal disturbances like anorexia, nausea, vomiting, abdominal discomfort and diarrhoea are known adverse effects of rifampicin. We report an upper gastrointestinal bleeding due to haemorrhagic gastric erosions after ingestion of rifampicin for pulmonary tuberculosis. The cause and effect relationship between development of haemorrhagic gastric erosions and rifampicin administration was confirmed by rechallenge with rifampicin. To our knowledge no such adverse effect of rifampicin has been reported previously.

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Year:  1990        PMID： 2385557      PMCID： PMC2429401          DOI： 10.1136/pgmj.66.774.310

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  6 in total

1.  Cytoprotection by prostaglandins.

Authors:  A Robert
Journal:  Gastroenterology       Date:  1979-10       Impact factor: 22.682

Review 2.  Adverse reactions to rifampicin in antituberculosis regimens.

Authors:  D J Girling
Journal:  J Antimicrob Chemother       Date:  1977-03       Impact factor: 5.790

3.  Rifampicin hepatitis. A clinical and histological study.

Authors:  P J Scheuer; J A Summerfield; S Lal; S Sherlock
Journal:  Lancet       Date:  1974-03-16       Impact factor: 79.321

4.  Sensitivity to rifampicin: incidence, mechanism, and prevention.

Authors:  J C Pujet; J C Homberg; G Decroix
Journal:  Br Med J       Date:  1974-05-25

5.  Adverse effects of antituberculosis drugs.

Authors:  D J Girling
Journal:  Drugs       Date:  1982 Jan-Feb       Impact factor: 9.546

6.  Drug-induced gastric mucosal injury.

Authors:  D Fromm
Journal:  World J Surg       Date:  1981-03       Impact factor: 3.352
  6 in total
  2 in total

1.  Early Detection of Acute Drug-Induced Liver Injury in Mice by Noninvasive Near-Infrared Fluorescence Imaging.

Authors:  Kristine O Vasquez; Jeffrey D Peterson
Journal:  J Pharmacol Exp Ther       Date:  2017-01-23       Impact factor: 4.030

2.  Inclusion Complexes of Rifampicin with Native and Derivatized Cyclodextrins: In Silico Modeling, Formulation, and Characterization.

Authors:  Qonita Kurnia Anjani; Juan Domínguez-Robles; Emilia Utomo; María Font; María Cristina Martínez-Ohárriz; Andi Dian Permana; Álvaro Cárcamo-Martínez; Eneko Larrañeta; Ryan F Donnelly
Journal:  Pharmaceuticals (Basel)       Date:  2021-12-24
  2 in total

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