Literature DB >> 23852566

Enantio- and regioselective conjugate addition of organometallic reagents to linear polyconjugated nitroolefins.

Matthieu Tissot1, Alexandre Alexakis.   

Abstract

The copper-catalysed conjugate addition of trialkylaluminium and dialkylzinc reagents to polyconjugated nitroolefins (nitrodiene and nitroenyne derivatives) is reported. A reversed Josiphos ligand L7 allows for the selective 1,4- or 1,6-addition with high enantioselectivities.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  asymmetric catalysis; conjugate addition; copper; ligand effects; phosphine ligands

Year:  2013        PMID： 23852566     DOI： 10.1002/chem.201300538

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  3 in total

1.  Racemic Vinylallenes in Catalytic Enantioselective Multicomponent Processes: Rapid Generation of Complexity through 1,6-Conjugate Additions.

Authors:  Youming Huang; Sebastian Torker; Xinghan Li; Juan Del Pozo; Amir H Hoveyda
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-06       Impact factor: 15.336

2.  Catalytic enantioselective 1,6-conjugate additions of propargyl and allyl groups.

Authors:  Fanke Meng; Xiben Li; Sebastian Torker; Ying Shi; Xiao Shen; Amir H Hoveyda
Journal:  Nature       Date:  2016-08-01       Impact factor: 49.962

3.  Preparation of spiro[indole-3,5'-isoxazoles] via Grignard conjugate addition/spirocyclization sequence.

Authors:  Alexander V Aksenov; Dmitrii A Aksenov; Nicolai A Aksenov; Anton A Skomorokhov; Elena V Aleksandrova; Michael Rubin
Journal:  RSC Adv       Date:  2021-01-06       Impact factor: 3.361
  3 in total

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