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Literature DB >> 23851980

Investigation of macrophage polarization using bone marrow derived macrophages.

Wei Ying¹, Patali S Cheruku, Fuller W Bazer, Stephen H Safe, Beiyan Zhou.

Abstract

The article describes a readily easy adaptive in vitro model to investigate macrophage polarization. In the presence of GM-CSF/M-CSF, hematopoietic stem/progenitor cells from the bone marrow are directed into monocytic differentiation, followed by M1 or M2 stimulation. The activation status can be tracked by changes in cell surface antigens, gene expression and cell signaling pathways.

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Year: 2013 PMID： 23851980 PMCID： PMC3728835 DOI： 10.3791/50323

Source DB: PubMed Journal: J Vis Exp ISSN： 1940-087X Impact factor: 1.355

20 in total

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Journal: Cell Metab Date: 2008-06 Impact factor: 27.287

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Journal: Cell Metab Date: 2008-06 Impact factor: 27.287

8. Regulation of murine mononuclear phagocyte inflammatory products by macrophage colony-stimulating factor. Lack of IL-1 and prostaglandin E2 production and generation of a specific IL-1 inhibitor.

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Authors: David M Mosser; Justin P Edwards
Journal: Nat Rev Immunol Date: 2008-12 Impact factor: 53.106

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95 in total

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4. Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.

Authors: Heng Li; Chen Fan; Chunlan Feng; Yanwei Wu; Huimin Lu; Peilan He; Xiaoqian Yang; Fenghua Zhu; Qing Qi; Yuanzhuo Gao; Jianping Zuo; Wei Tang
Journal: Br J Pharmacol Date: 2019-05-17 Impact factor: 8.739

5. Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages.

Authors: Yi Zhou; Xueqing Yu; Huimei Chen; Sara Sjöberg; Joséphine Roux; Lijun Zhang; Al-Habib Ivoulsou; Farid Bensaid; Cong-Lin Liu; Jian Liu; Joan Tordjman; Karine Clement; Chih-Hao Lee; Gokhan S Hotamisligil; Peter Libby; Guo-Ping Shi
Journal: Cell Metab Date: 2015-10-17 Impact factor: 27.287

6. Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms.

Authors: Yelena Kravtsova-Ivantsiv; Gilad Goldhirsh; Alexandra Ivantsiv; Ofer Ben Itzhak; Yong Tae Kwon; Eli Pikarsky; Aaron Ciechanover
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7. Intestinal stem cell growth and differentiation on a tubular scaffold with evaluation in small and large animals.

Authors: Shahab A Shaffiey; Hongpeng Jia; Timothy Keane; Cait Costello; Deena Wasserman; Maria Quidgley; Jenna Dziki; Stephen Badylak; Chhinder P Sodhi; John C March; David J Hackam
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8. MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.

Authors: Wei Ying; Alexander Tseng; Richard Cheng-An Chang; Andrew Morin; Tyler Brehm; Karen Triff; Vijayalekshmi Nair; Guoqing Zhuang; Hui Song; Srikanth Kanameni; Haiqing Wang; Michael C Golding; Fuller W Bazer; Robert S Chapkin; Stephen Safe; Beiyan Zhou
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9. FABP4/aP2 Regulates Macrophage Redox Signaling and Inflammasome Activation via Control of UCP2.

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Review 10. Pathogenesis of Kupffer Cells in Cholestatic Liver Injury.

Authors: Keisaku Sato; Chad Hall; Shannon Glaser; Heather Francis; Fanyin Meng; Gianfranco Alpini
Journal: Am J Pathol Date: 2016-07-22 Impact factor: 4.307