Literature DB >> 23849544

Casbane diterpenoids from the roots of Euphorbia pekinensis.

Wei-Wei Tao1, Jin-Ao Duan, Yu-Ping Tang, Nian-Yun Yang, Jian-Ping Li, Ye-Fei Qian.   

Abstract

Four casbane diterpenoids, together with three known related compounds were isolated from the roots of Euphorbia pekinensis. Their structures were elucidated on the basis of spectroscopic studies and comparison with the known related compounds. In addition, the absolute configuration of three compounds was determined by the modified Mosher's method. The isolated compounds were evaluated for their cytotoxic activity against seven human cancer cell lines by a WST-8 assay.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cancer cell lines; Casbane diterpenoid; Cytotoxic activity; Euphorbia pekinensis; Euphorbiaceae

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Year:  2013        PMID： 23849544     DOI： 10.1016/j.phytochem.2013.06.009

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  6 in total

1.  Antifeedant and Antiviral Diterpenoids from the Fresh Roots of Euphorbia jolkinii.

Authors:  Chun-Shuai Huang; Shi-Hong Luo; Yao-Lan Li; Chun-Huan Li; Juan Hua; Yan Liu; Shu-Xi Jing; Ying Wang; Min-Jie Yang; Sheng-Hong Li
Journal:  Nat Prod Bioprospect       Date:  2014-04-09

2.  Toxicity of Pekinenin C from Euphorbia Pekinensis Radix on Rat Small Intestinal Crypt Epithelial Cell and Its Apoptotic Mechanism.

Authors:  Yudan Cao; Fangfang Cheng; Weifeng Yao; Beihua Bao; Kaicheng Zhang; Li Zhang; Anwei Ding
Journal:  Int J Mol Sci       Date:  2016-06-02       Impact factor: 5.923

3.  Pekinenin E Inhibits the Growth of Hepatocellular Carcinoma by Promoting Endoplasmic Reticulum Stress Mediated Cell Death.

Authors:  Lu Fan; Qingling Xiao; Yanyan Chen; Gang Chen; Jinao Duan; Weiwei Tao
Journal:  Front Pharmacol       Date:  2017-06-29       Impact factor: 5.810

4.  Laxative Effects of Total Diterpenoids Extracted from the Roots of Euphorbia pekinensis Are Attributable to Alterations of Aquaporins in the Colon.

Authors:  Kuilong Wang; Lian Liu; Jianyu Huang; Hongli Yu; Hao Wu; Yu Duan; Xiaobing Cui; Xingde Zhang; Liping Liu; Wei Wang
Journal:  Molecules       Date:  2017-03-14       Impact factor: 4.411

5.  Collective Total Synthesis of Casbane Diterpenes: One Strategy, Multiple Targets.

Authors:  Lorenz E Löffler; Conny Wirtz; Alois Fürstner
Journal:  Angew Chem Int Ed Engl       Date:  2021-01-28       Impact factor: 15.336

6.  In vitro and in vivo assessment of CYP2C9-mediated herb-herb interaction of Euphorbiae Pekinensis Radix and Glycyrrhizae Radix.

Authors:  Xinmin Wang; Yunru Peng; Xinyue Jing; Dawei Qian; Yuping Tang; Jin-Ao Duan
Journal:  Front Pharmacol       Date:  2014-08-22       Impact factor: 5.810
  6 in total

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