Literature DB >> 23849276

AIDS treatment and mental health: evidence from Uganda.

Edward N Okeke1, Glenn J Wagner.   

Abstract

Increased access to antiretroviral therapy (ART) in developing countries over the last decade is believed to have contributed to reductions in HIV transmission and improvements in life expectancy. While numerous studies document the effects of ART on physical health and functioning, comparatively less attention has been paid to the effects of ART on mental health outcomes. In this paper we study the impact of ART on depression in a cohort of patients in Uganda entering HIV care. We find that 12 months after beginning ART, the prevalence of major and minor depression in the treatment group had fallen by approximately 15 and 27 percentage points respectively relative to a comparison group of patients in HIV care but not receiving ART. We also find some evidence that ART helps to close the well-known gender gap in depression between men and women.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Africa; Antiretroviral therapy; HIV; Mental health

Mesh:

Substances:

Year:  2013        PMID: 23849276      PMCID: PMC3713499          DOI: 10.1016/j.socscimed.2013.05.018

Source DB:  PubMed          Journal:  Soc Sci Med        ISSN: 0277-9536            Impact factor:   4.634


  33 in total

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Authors:  Melvyn Freeman; Vikram Patel; Pamela Y Collins; Jose Bertolote
Journal:  Br J Psychiatry       Date:  2005-07       Impact factor: 9.319

2.  Depressive symptoms increase risk of HIV disease progression and mortality among women in Tanzania.

Authors:  Gretchen Antelman; Sylvia Kaaya; Ruilan Wei; Jessie Mbwambo; Gernard I Msamanga; Wafaie W Fawzi; Mary C Smith Fawzi
Journal:  J Acquir Immune Defic Syndr       Date:  2007-04-01       Impact factor: 3.731

3.  Quasi-experimental evidence on the causal effects of physical health on mental health.

Authors:  Manoj Mohanan; Joanna Maselko
Journal:  Int J Epidemiol       Date:  2009-11-24       Impact factor: 7.196

4.  The PHQ-9: validity of a brief depression severity measure.

Authors:  K Kroenke; R L Spitzer; J B Williams
Journal:  J Gen Intern Med       Date:  2001-09       Impact factor: 5.128

5.  Depression and health related quality of life among HIV-infected people.

Authors:  L S Briongos-Figuero; P Bachiller-Luque; T Palacios-Martín; D De Luis-Román; J M Eiros-Bouza
Journal:  Eur Rev Med Pharmacol Sci       Date:  2011-08       Impact factor: 3.507

6.  An investigation into the health-related quality of life of individuals living with HIV who are receiving HAART.

Authors:  J Jelsma; E Maclean; J Hughes; X Tinise; M Darder
Journal:  AIDS Care       Date:  2005-07

7.  The quality of life of HIV-infected women is associated with psychiatric morbidity.

Authors:  M A Tostes; M Chalub; N J Botega
Journal:  AIDS Care       Date:  2004-02

8.  Factors associated with prevalence of mental disorder in people living with HIV/AIDS in South Africa.

Authors:  M Freeman; N Nkomo; Z Kafaar; K Kelly
Journal:  AIDS Care       Date:  2007-11

9.  Depressive symptoms and AIDS-related mortality among a multisite cohort of HIV-positive women.

Authors:  Judith A Cook; Dennis Grey; Jane Burke; Mardge H Cohen; Alejandra C Gurtman; Jean L Richardson; Tracey E Wilson; Mary A Young; Nancy A Hessol
Journal:  Am J Public Health       Date:  2004-07       Impact factor: 9.308

10.  How Uganda reversed its HIV epidemic.

Authors:  Gary Slutkin; Sam Okware; Warren Naamara; Don Sutherland; Donna Flanagan; Michel Carael; Erik Blas; Paul Delay; Daniel Tarantola
Journal:  AIDS Behav       Date:  2006-07
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  11 in total

Review 1.  Reliability and validity of depression assessment among persons with HIV in sub-Saharan Africa: systematic review and meta-analysis.

Authors:  Alexander C Tsai
Journal:  J Acquir Immune Defic Syndr       Date:  2014-08-15       Impact factor: 3.731

2.  The indirect impact of antiretroviral therapy: Mortality risk, mental health, and HIV-negative labor supply.

Authors:  Victoria Baranov; Daniel Bennett; Hans-Peter Kohler
Journal:  J Health Econ       Date:  2015-08-24       Impact factor: 3.883

3.  Burden of Depression in Outpatient HIV-Infected adults in Sub-Saharan Africa; Systematic Review and Meta-analysis.

Authors:  S M Lofgren; D J Bond; N Nakasujja; D R Boulware
Journal:  AIDS Behav       Date:  2020-06

4.  Prevalence of depression in Uganda: A systematic review and meta-analysis.

Authors:  Mark Mohan Kaggwa; Sarah Maria Najjuka; Felix Bongomin; Mohammed A Mamun; Mark D Griffiths
Journal:  PLoS One       Date:  2022-10-20       Impact factor: 3.752

5.  Project THANKS: Examining HIV/AIDS-Related Barriers and Facilitators to Care in African American Women: A Community Perspective.

Authors:  Ndidiamaka Amutah-Onukagha; Meena Mahadevan; Ijeoma Opara; Monica Rodriguez; Megan Trusdell; Jessica Kelly
Journal:  AIDS Patient Care STDS       Date:  2018-04       Impact factor: 5.078

6.  Linkage to HIV care, postpartum depression, and HIV-related stigma in newly diagnosed pregnant women living with HIV in Kenya: a longitudinal observational study.

Authors:  Bulent Turan; Kristi L Stringer; Maricianah Onono; Elizabeth A Bukusi; Sheri D Weiser; Craig R Cohen; Janet M Turan
Journal:  BMC Pregnancy Childbirth       Date:  2014-12-03       Impact factor: 3.007

7.  Depression during pregnancy and the postpartum among HIV-infected women on antiretroviral therapy in Uganda.

Authors:  Angela Kaida; Lynn T Matthews; Scholastic Ashaba; Alexander C Tsai; Steve Kanters; Magdalena Robak; Christina Psaros; Jerome Kabakyenga; Yap Boum; Jessica E Haberer; Jeffrey N Martin; Peter W Hunt; David R Bangsberg
Journal:  J Acquir Immune Defic Syndr       Date:  2014-12-01       Impact factor: 3.731

8.  Contextualization of psychological treatments for government health systems in low-resource settings: group interpersonal psychotherapy for caregivers of children with nodding syndrome in Uganda.

Authors:  Byamah B Mutamba; Brandon A Kohrt; James Okello; Janet Nakigudde; Bernard Opar; Seggane Musisi; William Bazeyo; Joop de Jong
Journal:  Implement Sci       Date:  2018-06-28       Impact factor: 7.327

9.  Body and mind: retention in antiretroviral treatment care is improved by mental health training of care providers in Ethiopia.

Authors:  Tezera Moshago Berheto; Sven Gudmund Hinderaker; Mbazi Senkoro; Hannock Tweya; Tekalign Deressa; Yimam Getaneh; Gulilat Gezahegn
Journal:  BMC Public Health       Date:  2018-07-20       Impact factor: 3.295

10.  Prevalence of depression among HIV-positive pregnant women and its association with adherence to antiretroviral therapy in Addis Ababa, Ethiopia.

Authors:  Workeabeba Abebe; Mahlet Gebremariam; Mitike Molla; Solomon Teferra; Larry Wissow; Andrea Ruff
Journal:  PLoS One       Date:  2022-01-20       Impact factor: 3.240

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