Literature DB >> 23848133

Indocyanine green angiographic and optical coherence tomographic findings support classification of polypoidal choroidal vasculopathy into two types.

Akiyuki Kawamura1, Mitsuko Yuzawa, Ryusaburo Mori, Miho Haruyama, Koji Tanaka.   

Abstract

PURPOSE: We assessed the characteristic indocyanine green angiographic (ICGA) and spectral domain optical coherence tomographic (SD-OCT) findings of two types of polypoidal choroidal vasculopathy (PCV), distinguishable by different filling patterns on ICGA.
METHODS: Thirty-one eyes with PCV were classified into types 1 and 2 based on ICGA findings of either the presence or absence of both a feeder and a draining vessel. Characteristic ICGA findings were evaluated for each type of PCV. Spectral domain optical coherence tomographic images of the 31 eyes were also used to compare the two types of PCV.
RESULTS: Both a feeder and a draining vessel were observed in 13 eyes (type 1). Eighteen eyes had neither feeder nor draining vessels (type 2). In PCV type 1, a break in the highly reflective line thought to be Bruch's membrane was detected, corresponding to the feeder vessel in-growth site on SD-OCT. This line was straight. In PCV type 2, the highly reflective line exhibited irregular thickness and had highly reflective substances adhering to its lower portion. It curved downward and became increasingly obscure, ultimately disappearing at a point corresponding to the site at which network vessel filling began. The mean subfoveal choroidal thicknesses in eyes with PCV type 1 and PCV type 2 were 199 ± 65 and 288 ± 98 μm, respectively.
CONCLUSIONS: Our observations support the existence of two distinct types of PCV. The first type represents choroidal neovascularization, whilst the second type involves choroidal vasculature abnormalities.
© 2013 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  choroidal neovascularization; choroidal vasculature abnormality; indocyanine green angiography; optical coherence tomography; polypoidal choroidal vasculopathy

Mesh:

Substances:

Year:  2013        PMID: 23848133     DOI: 10.1111/aos.12110

Source DB:  PubMed          Journal:  Acta Ophthalmol        ISSN: 1755-375X            Impact factor:   3.761


  36 in total

1.  [Sensitivity and specificity of optical coherence tomography in diagnosing polypoidal choroidal vasculopathy].

Authors:  Yi Zhang; Jing Yao; Xiao-Hua Wang; Lin Zhao; Li-Jun Wang; Jian-Ming Wang; Ai-Yi Zhou
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2016-02-20

2.  Comment on "Assessment of the long-term visual and anatomical outcomes of ranibizumab to treat neovascular age-related macular degeneration".

Authors:  Dan Călugăru; Mihai Călugăru
Journal:  Int J Ophthalmol       Date:  2018-11-18       Impact factor: 1.779

3.  Optical Coherence Tomography-based Diagnosis of Polypoidal Choroidal Vasculopathy in Korean Patients.

Authors:  Young Suk Chang; Jae Hui Kim; Jong Woo Kim; Tae Gon Lee; Chul Gu Kim
Journal:  Korean J Ophthalmol       Date:  2016-05-18

4.  Analysis of choroidal morphology and comparison of imaging findings of subtypes of polypoidal choroidal vasculopathy: a new classification system.

Authors:  Zi-Yang Liu; Bing Li; Song Xia; You-Xin Chen
Journal:  Int J Ophthalmol       Date:  2020-05-18       Impact factor: 1.779

5.  Proteolytic Degradation and Inflammation Play Critical Roles in Polypoidal Choroidal Vasculopathy.

Authors:  Sandeep Kumar; Hiroyuki Nakashizuka; Alex Jones; Alyssia Lambert; Xuchen Zhao; Megan Shen; Mackenzie Parker; Shixian Wang; Zachary Berriochoa; Amrita Fnu; Stephanie VanBeuge; Patricia Chévez-Barrios; Mark Tso; Jon Rainier; Yingbin Fu
Journal:  Am J Pathol       Date:  2017-09-21       Impact factor: 4.307

6.  Two-year results of a treat-and-extend regimen with aflibercept for polypoidal choroidal vasculopathy.

Authors:  Dan Călugăru; Mihai Călugăru
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2017-08-21       Impact factor: 3.117

7.  Reply to the letter to the editor: Two-year results of treat-and-extend regimen with aflibercept for polypoidal choroidal vasculopathy.

Authors:  Masahiro Morimoto; Hidetaka Matsumoto; Kensuke Mimura; Hideo Akiyama
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2017-08-25       Impact factor: 3.117

8.  Effects of photodynamic therapy plus intravitreal aflibercept with subtenon triamcinolone injections for aflibercept-resistant polypoidal choroidal vasculopathy.

Authors:  Dan Călugăru; Mihai Călugăru
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2017-09-06       Impact factor: 3.117

9.  Comment on "Intravitreal conbercept injection for neovascular age-related macular degeneration".

Authors:  Dan Călugăru; Mihai Călugăru
Journal:  Int J Ophthalmol       Date:  2020-02-18       Impact factor: 1.779

10.  Optical coherence tomography angiography in patients with polypoidal choroidal vasculopathy.

Authors:  Ju Young Kim; Oh Woong Kwon; Hyun Sub Oh; Soon Hyun Kim; Yong Sung You
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-11-30       Impact factor: 3.117

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