Literature DB >> 2384739

Azathioprine and allopurinol: a potentially dangerous combination.

G Venkat Raman1, V L Sharman, H A Lee.   

Abstract

We report the association of leucopenia and anaemia in five patients given a combination of azathioprine and allopurinol. Three subjects were renal transplant recipients with mild to moderate impairment of graft function. The complication appeared between 4 and 6 weeks following initiation of the combination therapy. Discontinuation of one of the two drugs resulted in full recovery within 4-8 weeks.

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Year:  1990        PMID: 2384739     DOI: 10.1111/j.1365-2796.1990.tb00195.x

Source DB:  PubMed          Journal:  J Intern Med        ISSN: 0954-6820            Impact factor:   8.989


  18 in total

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Review 5.  The challenges of gout management in the elderly.

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Review 6.  Urate-lowering therapy: current options and future prospects for elderly patients with gout.

Authors:  Lisa K Stamp; Peter T Chapman
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8.  Use of allopurinol to optimize thiopurine immunomodulator efficacy in inflammatory bowel disease.

Authors:  Miles P Sparrow
Journal:  Gastroenterol Hepatol (N Y)       Date:  2008-07

Review 9.  Use of febuxostat in the management of gout in the United Kingdom.

Authors:  Arabella Waller; Kelsey M Jordan
Journal:  Ther Adv Musculoskelet Dis       Date:  2016-12-28       Impact factor: 5.346

10.  The long-term risk of continuous immunosuppression using thioguanides in inflammatory bowel disease.

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Journal:  Ther Adv Chronic Dis       Date:  2010-01       Impact factor: 5.091

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