Literature DB >> 23846919

BRCA and pancreatic cancer.

Gregory T Brennan1, Valerie Relias, Muhammad Wasif Saif.   

Abstract

Germline mutations in BRCA genes have been associated with pancreatic cancer. Laboratory and clinical data suggest that patients with BRCA mutations may be more responsive to therapy consisting of conventional chemotherapy with a poly(ADP-ribose) polymerase inhibitor (PARPi). The most recent data from the 2013 American Society of Clinical Oncology (ASCO) Annual Meeting will be reviewed (Abstracts #11024 and #TPS4144).

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 23846919     DOI: 10.6092/1590-8577/1652

Source DB:  PubMed          Journal:  JOP        ISSN: 1590-8577


  5 in total

1.  gDNA enrichment by a transposase-based technology for NGS analysis of the whole sequence of BRCA1, BRCA2, and 9 genes involved in DNA damage repair.

Authors:  Sandy Chevrier; Romain Boidot
Journal:  J Vis Exp       Date:  2014-10-06       Impact factor: 1.355

2.  Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts.

Authors:  Wei Zhan; Celeste A Shelton; Phil J Greer; Randall E Brand; David C Whitcomb
Journal:  Pancreas       Date:  2018-09       Impact factor: 3.327

Review 3.  The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms.

Authors:  Saswati Chand; Kevin O'Hayer; Fernando F Blanco; Jordan M Winter; Jonathan R Brody
Journal:  Int J Biol Sci       Date:  2016-01-27       Impact factor: 6.580

4.  Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma.

Authors:  Qiqing Sun; Wenyan Xu; Shunrong Ji; Yi Qin; Wensheng Liu; Qiangsheng Hu; Zheng Zhang; Mengqi Liu; Xianjun Yu; Xiaowu Xu
Journal:  Cancer Cell Int       Date:  2019-03-04       Impact factor: 5.722

5.  Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.

Authors:  Parisa Momtaz; Catherine A O'Connor; Joanne F Chou; Marinela Capanu; Wungki Park; Chaitanya Bandlamudi; Michael F Berger; David P Kelsen; Sarah P Suehnholz; Debyani Chakravarty; Kenneth H Yu; Anna M Varghese; Alice Zervoudakis; Jia Li; Geoffrey Y Ku; Jennifer S Park; Marina Shcherba; James J Harding; Zoe Goldberg; Ghassan K Abou-Alfa; Erin E Salo-Mullen; Zsofia K Stadler; Christine A Iacobuzio-Donahue; Eileen M O'Reilly
Journal:  Cancer       Date:  2021-08-05       Impact factor: 6.921

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.