OBJECTIVES: Renal osteodystrophy (RO) are skeletal abnormalities seen in patients with secondary hyperparathyroidism (SHPT). This study aims to evaluate the effects of RO using panoramic radiography parameters. Furthermore, the correlation between these parameters and parathyroid hormone (PTH) levels was tested. MATERIALS AND METHODS: Qualitative (mandibular cortical index/trabecular bone pattern) and quantitative parameters (mental index/calcification and resorption foci) were applied from panoramic radiographs of chronic kidney disease (CKD) patients and controls. Frequency distribution and descriptive analysis were used to compare the results of both groups. Spearman's correlation coefficient evaluated the correlation between serum PTH levels of CKD patients and the radiographic parameters. Intra- and interobserver agreement was tested using the intraclass correlation coefficient and kappa index. RESULTS: Intra- and interobserver agreement was respectively excellent (0.81-1.00) and good (0.61-0.80). Qualitative parameters demonstrate significant difference compared with the control group. Mean mental index was lower in patients with CKD (3.17 ± 1.35 mm), but the difference was not significant. Calcification/resorption foci (3.63 ± 2.07) of CKD patients were significantly more present than in the control group (p = 0.0001). PTH levels were correlated with mental index, mandibular cortical index and trabecular bone pattern (respectively, 0.0034, 0.0315, and 0.0370). CONCLUSIONS: RO presented a number of characteristic bone metabolic effects in the jaws that could be observed on panoramic radiographs. Radiographs of CKD patients demonstrate significantly more calcification and resorption. CLINICAL RELEVANCE: The mental index, mandibular cortical index, and trabecular bone pattern are good parameters for evaluating the effects of RO on severe secondary hyperparathyroidism.
OBJECTIVES:Renal osteodystrophy (RO) are skeletal abnormalities seen in patients with secondary hyperparathyroidism (SHPT). This study aims to evaluate the effects of RO using panoramic radiography parameters. Furthermore, the correlation between these parameters and parathyroid hormone (PTH) levels was tested. MATERIALS AND METHODS: Qualitative (mandibular cortical index/trabecular bone pattern) and quantitative parameters (mental index/calcification and resorption foci) were applied from panoramic radiographs of chronic kidney disease (CKD) patients and controls. Frequency distribution and descriptive analysis were used to compare the results of both groups. Spearman's correlation coefficient evaluated the correlation between serum PTH levels of CKDpatients and the radiographic parameters. Intra- and interobserver agreement was tested using the intraclass correlation coefficient and kappa index. RESULTS: Intra- and interobserver agreement was respectively excellent (0.81-1.00) and good (0.61-0.80). Qualitative parameters demonstrate significant difference compared with the control group. Mean mental index was lower in patients with CKD (3.17 ± 1.35 mm), but the difference was not significant. Calcification/resorption foci (3.63 ± 2.07) of CKDpatients were significantly more present than in the control group (p = 0.0001). PTH levels were correlated with mental index, mandibular cortical index and trabecular bone pattern (respectively, 0.0034, 0.0315, and 0.0370). CONCLUSIONS: RO presented a number of characteristic bone metabolic effects in the jaws that could be observed on panoramic radiographs. Radiographs of CKDpatients demonstrate significantly more calcification and resorption. CLINICAL RELEVANCE: The mental index, mandibular cortical index, and trabecular bone pattern are good parameters for evaluating the effects of RO on severe secondary hyperparathyroidism.
Authors: A Taguchi; M Ohtsuka; T Nakamoto; K Naito; M Tsuda; Y Kudo; E Motoyama; Y Suei; K Tanimoto Journal: Dentomaxillofac Radiol Date: 2007-03 Impact factor: 2.419
Authors: André Ferreira Leite; Paulo Tadeu de Souza Figueiredo; Cláudio Mares Guia; Nilce Santos Melo; Ana Patrícia de Paula Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Date: 2010-03
Authors: Christina Lindh; Keith Horner; Grethe Jonasson; Peter Olsson; Madeleine Rohlin; Reinhilde Jacobs; Kety Karayianni; Paul van der Stelt; Judith Adams; Elizabeth Marjanovic; Sue Pavitt; Hugh Devlin Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Date: 2008-03-04
Authors: Stenio Medeiros Queiroz; Ana Luiza Dias Leite De Andrade; Patrícia Teixeira De Oliveira; Paulo Raphael Leite Maia; Ângelo Giuseppe Roncalli Da Costa Oliveira; Roseana De Almeida Freitas; Hébel Cavalcanti Galvão Journal: Eur J Dent Date: 2019-12-03