Literature DB >> 23845649

Topical Mitomycin C application for esophageal stricture: safe, precise, and novel endoscopic technique.

Khaled Mohamed El-Asmar1.   

Abstract

PURPOSE: The first line of management of benign esophageal stricture is endoscopic dilatation; however, multiple sessions are usually indicated especially in resistant cases. Topical Mitomycin C (MCC) application is a new adjuvant treatment in the management of esophageal stricture with promising results in different case series. Several techniques have been reported for application; nevertheless, the ideal technique has not been described yet.
MATERIAL AND METHODS: In this series we have devised a new technique using both the flexible and the rigid endoscope and a specially designed Nelaton catheter.
RESULTS: This technique was applied in 38 sessions for 16 caustic esophageal strictures with technical success in all cases. No procedure-related complications were observed in this series.
CONCLUSION: This novel technique is feasible and effective and can be considered as standard for topical MMC application on esophageal stricture.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Endoluminal drug delivery; Endoscopic dilatation; Esophageal stricture; MMC; Mitomycin C; Mitomycin C application technique

Mesh:

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Year:  2013        PMID: 23845649     DOI: 10.1016/j.jpedsurg.2013.03.069

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  1 in total

1.  Ingested sharp foreign body presented as chronic esophageal stricture and inflammatory mediastinal mass for 113 weeks: Case report.

Authors:  Nour A Tashtush; Ziad A Bataineh; Dawood H Yusef; Thekraiat M Al Quran; Liqa A Rousan; Ruba Khasawneh; Abdelwahab J Aleshawi; Eyad M Altamimi
Journal:  Ann Med Surg (Lond)       Date:  2019-08-01
  1 in total

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