OBJECTIVE: To evaluate the significance of umbilical cord chitotriosidase concentrations in pregnancies with mild preeclampsia and explore the relationship between fetal chitotriosidase levels and fetal blood flow velocity. METHOD: The study population included control group (n=40) and study group with mild preeclampsia (n=40). Umbilical cord blood samples were collected immediately after delivery. Umbilical artery (UA) flow velocity waveform was determined just before delivery. RESULTS: Umbilical cord chitotriosidase levels and UA S/D rate were significantly high in preeclamptic group. CONCLUSION: Chitotriosidase may be useful biochemical marker of fetal compromise that reflects the severity of fetoplacental blood flow resistance in pregnancies complicated by preeclampsia.
OBJECTIVE: To evaluate the significance of umbilical cord chitotriosidase concentrations in pregnancies with mild preeclampsia and explore the relationship between fetal chitotriosidase levels and fetal blood flow velocity. METHOD: The study population included control group (n=40) and study group with mild preeclampsia (n=40). Umbilical cord blood samples were collected immediately after delivery. Umbilical artery (UA) flow velocity waveform was determined just before delivery. RESULTS: Umbilical cord chitotriosidase levels and UA S/D rate were significantly high in preeclamptic group. CONCLUSION: Chitotriosidase may be useful biochemical marker of fetal compromise that reflects the severity of fetoplacental blood flow resistance in pregnancies complicated by preeclampsia.