Literature DB >> 23839913

Enhanced efficacy and broadening of antibacterial action of drugs via the use of capped mesoporous nanoparticles.

Núria Mas1, Irene Galiana, Laura Mondragón, Elena Aznar, Estela Climent, Nuria Cabedo, Félix Sancenón, José Ramón Murguía, Ramón Martínez-Máñez, María D Marcos, Pedro Amorós.   

Abstract

Bug busters: A novel nanodevice consisting of mesoporous nanoparticles loaded with vancomycin and capped with ε-poly-L-lysine (ε-PL) was prepared and its interaction with different Gram-negative bacteria studied. A remarkable improvement in the efficacy of the antimicrobial drug ε-PL and a broadening of the antimicrobial spectrum of vancomycin is demonstrated.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  gated materials; mesoporous materials; nanoparticles; vancomycin; ε-poly-L-lysine

Mesh：

Substances：

Year:  2013        PMID： 23839913     DOI： 10.1002/chem.201302170

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  6 in total

Review 1.  Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

Authors:  María Vallet-Regí; Ferdi Schüth; Daniel Lozano; Montserrat Colilla; Miguel Manzano
Journal:  Chem Soc Rev       Date:  2022-07-04       Impact factor: 60.615

2.  Encapsulation of Anti-Tuberculosis Drugs within Mesoporous Silica and Intracellular Antibacterial Activities.

Authors:  Xin Xia; Kevin Pethe; Ryangyeo Kim; Lluis Ballell; David Barros; Jonathan Cechetto; HeeKyoung Jeon; Kideok Kim; Alfonso E Garcia-Bennett
Journal:  Nanomaterials (Basel)       Date:  2014-09-11       Impact factor: 5.076

3.  The anti-fasciolasis properties of silver nanoparticles produced by Trichoderma harzianum and their improvement of the anti-fasciolasis drug triclabendazole.

Authors:  Youssuf A Gherbawy; Ismail M Shalaby; Mahmoud Syed Abd El-Sadek; Hesham M Elhariry; Banaja A Abdelilah
Journal:  Int J Mol Sci       Date:  2013-11-05       Impact factor: 5.923

Review 4.  Targeted Stimuli-Responsive Mesoporous Silica Nanoparticles for Bacterial Infection Treatment.

Authors:  Montserrat Colilla; María Vallet-Regí
Journal:  Int J Mol Sci       Date:  2020-11-15       Impact factor: 5.923

5.  Green Algae as a Drug Delivery System for the Controlled Release of Antibiotics.

Authors:  Inga S Shchelik; Simon Sieber; Karl Gademann
Journal:  Chemistry       Date:  2020-11-18       Impact factor: 5.236

Review 6.  Nanoantibiotics Based in Mesoporous Silica Nanoparticles: New Formulations for Bacterial Infection Treatment.

Authors:  Elena Álvarez; Blanca González; Daniel Lozano; Antonio L Doadrio; Montserrat Colilla; Isabel Izquierdo-Barba
Journal:  Pharmaceutics       Date:  2021-11-29       Impact factor: 6.321
  6 in total

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